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Pegrizeprument
(Synonyms: VEL-101, FR104) Copy Product Info
🥰Excellent
Synonyms: VEL-101, FR104
Catalog No. T77481 Copy Product Info
🥰Excellent
Pegrizeprument is a humanized monoclonal antibody targeting CD28, inhibiting effector T cells, reducing T and B cell responses to rhMOG.
Pegrizeprument
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $158 | - | In Stock | |
| 5 mg | $477 | - | In Stock | |
| 10 mg | $767 | - | In Stock | |
| 25 mg | $1,130 | - | In Stock | |
| 50 mg | Preferential | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:97.26% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Pegrizeprument is a humanized monoclonal antibody targeting CD28, inhibiting effector T cells, reducing T and B cell responses to rhMOG. |
| Targets & IC50 | T lymphocyte:0.10 μg/mL |
| In vitro | Pegrizeprument inhibited T lymphocyte proliferation in a dose-dependent manner in mixed lymphocyte response assay with IC50 = 0.10 μg/mL. |
| In vivo | In juvenile baboons, Pegrizeprument is given intravenously at 5 mg/kg and the half-life of elimination is 8.4 days. |
| Synonyms | VEL-101, FR104 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Pegol |
| Gene ID | |
| Uniprot ID | |
| Target | CD28 |
| Molecular Weight | 126.08 kDa |
| Isotype | Human IgG2 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Pegrizeprument in vivo | Pegrizeprument in vitro | Pegrizeprument molecular weight
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