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Pegrizeprument (Synonyms: VEL-101, FR104)

Catalog No. T77481 Copy Product Info
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Pegrizeprument is a humanized monoclonal antibody targeting CD28, inhibiting effector T cells, reducing T and B cell responses to rhMOG.

Pegrizeprument

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Catalog No. T77481
Synonyms VEL-101, FR104

Pegrizeprument is a humanized monoclonal antibody targeting CD28, inhibiting effector T cells, reducing T and B cell responses to rhMOG.

Pegrizeprument
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$197-In Stock
5 mg$596-In Stock
10 mg$959-In Stock
25 mg$1,420-In Stock
50 mg$1,920-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:97.26% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Pegrizeprument is a humanized monoclonal antibody targeting CD28, inhibiting effector T cells, reducing T and B cell responses to rhMOG.
Targets&IC50
T lymphocyte:0.10 μg/mL
In vitro
Pegrizeprument inhibited T lymphocyte proliferation in a dose-dependent manner in mixed lymphocyte response assay with IC50 = 0.10 μg/mL.
In vivo
In juvenile baboons, Pegrizeprument is given intravenously at 5 mg/kg and the half-life of elimination is 8.4 days.
SynonymsVEL-101, FR104
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetCD28
Chemical Properties
Molecular Weight126.08 kDa
Antibody Information
IsotypeHuman IgG2 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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