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FLT3-IN-32 TFA

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Catalog No. T212162Cas No. 3047195-49-0

FLT3-IN-32 TFA is a potent FLT3 inhibitor with IC50 values of 2.40 nM and 3.83 nM against FLT3-ITD and FLT3-D835Y, respectively. It effectively inhibits the proliferation/survival of human MV4-11 cells with an IC50 of 0.07 nM. FLT3-IN-32 TFA is applicable in acute myeloid leukemia (AML) research.

FLT3-IN-32 TFA
Other Forms of FLT3-IN-32 TFA:

FLT3-IN-32 TFA

😃Good
Catalog No. T212162Cas No. 3047195-49-0
FLT3-IN-32 TFA is a potent FLT3 inhibitor with IC50 values of 2.40 nM and 3.83 nM against FLT3-ITD and FLT3-D835Y, respectively. It effectively inhibits the proliferation/survival of human MV4-11 cells with an IC50 of 0.07 nM. FLT3-IN-32 TFA is applicable in acute myeloid leukemia (AML) research.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mgInquiry10-14 weeks10-14 weeks
50 mgInquiry10-14 weeks10-14 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
FLT3-IN-32 TFA is a potent FLT3 inhibitor with IC50 values of 2.40 nM and 3.83 nM against FLT3-ITD and FLT3-D835Y, respectively. It effectively inhibits the proliferation/survival of human MV4-11 cells with an IC50 of 0.07 nM. FLT3-IN-32 TFA is applicable in acute myeloid leukemia (AML) research.
In vitro
FLT3-IN-32 TFA (Compound 29b) demonstrates anti-proliferative activity against EOL-1 (IC50 = 0.02 nM), MOLM-13 (IC50 = 0.20 nM), MONO-MAC-1 (IC50 = 100 nM), and MONO-MAC-6 (IC50 = 0.65 nM).
Chemical Properties
Molecular Weight629.58
FormulaC30H30F3N5O7
Cas No.3047195-49-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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