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Tilvestamab
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Catalog No. T76723Cas No. 2226775-26-2
Alias BGB149, BGB 149
Tilvestamab (BGB149) is a humanized antibody targeting AXL with anti-tumor and anti-fibrotic activity, inhibiting Gas6-stimulated AXL activation and tumor progression in 786-0 RCC cells, used in cancer research.
Tilvestamab
Tilvestamab
😃Good
Catalog No. T76723Alias BGB149, BGB 149Cas No. 2226775-26-2
Tilvestamab (BGB149) is a humanized antibody targeting AXL with anti-tumor and anti-fibrotic activity, inhibiting Gas6-stimulated AXL activation and tumor progression in 786-0 RCC cells, used in cancer research.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $228 | In Stock | In Stock | |
| 5 mg | $556 | In Stock | In Stock | |
| 10 mg | $889 | - | In Stock | |
| 25 mg | $1,320 | - | In Stock | |
| 50 mg | $1,780 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:97.77% (SEC-HPLC)
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| Description | Tilvestamab (BGB149) is a humanized antibody targeting AXL with anti-tumor and anti-fibrotic activity, inhibiting Gas6-stimulated AXL activation and tumor progression in 786-0 RCC cells, used in cancer research. |
| In vivo | Tilvestamab (30 mg/kg twice weekly intraperitoneal injection) inhibited AXL and thus inhibited tumor growth in RCC mice in situ. [1] |
| Synonyms | BGB149, BGB 149 |
| Reactivity | Human |
| Verified Activity | Immobilized Human Axl Protein (ECD, Fc) at 2 μg/mL (30 μL/well) can bind Tilvestamab. The EC50 is 0.008241 μg/mL  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | AXL/UFO |
| Molecular Weight | 146.22 kDa |
| Cas No. | 2226775-26-2 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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