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Ginsenoside C-K hexapropionate ester (Structure 2) acts as a selective agonist for LXRα without significantly activating LXRβ. By stimulating LXRα, it enhances the expression of downstream genes such as ABCA1, facilitating reverse cholesterol transport and reducing lipid accumulation in macrophage-derived foam cells, making it useful for atherosclerosis research. This compound is a synthetic derivative, created by modifying the active metabolite of Panax notoginseng saponins, Ginsenoside Compound K, with propionic anhydride.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | Ginsenoside C-K hexapropionate ester (Structure 2) acts as a selective agonist for LXRα without significantly activating LXRβ. By stimulating LXRα, it enhances the expression of downstream genes such as ABCA1, facilitating reverse cholesterol transport and reducing lipid accumulation in macrophage-derived foam cells, making it useful for atherosclerosis research. This compound is a synthetic derivative, created by modifying the active metabolite of Panax notoginseng saponins, Ginsenoside Compound K, with propionic anhydride. |
| Molecular Weight | 959.27 |
| Formula | C54H86O14 |
| Cas No. | 2861254-89-7 |
| Smiles | C[C@]12[C@@]([C@@]([C@@](O[C@H]3[C@H](OC(CC)=O)[C@@H](OC(CC)=O)[C@H](OC(CC)=O)[C@@H](COC(CC)=O)O3)(CCC=C(C)C)C)(CC1)[H])([C@H](OC(CC)=O)C[C@]4([C@@]2(C)CC[C@@]5([C@]4(C)CC[C@H](OC(CC)=O)C5(C)C)[H])[H])[H] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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