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Sacituzumab tirumotecan (Synonyms: SKB264, SKB 264, MK-2870, MK2870)

Catalog No. T9901A-237 Copy Product Info
Purity: 99%
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Sacituzumab tirumotecan (SKB264) is an antibody-drug conjugate (ADC) targeting TROP2 (trophoblast cell surface antigen 2), capable of releasing the active payload KL610023 within TROP2-positive tumour cells. an effective topoisomerase I inhibitor that induces DNA damage and leads to cell cycle arrest and apoptosis, for use in non-small cell lung cancer (NSCLC) and triple-negative breast cancer (TNBC).

Sacituzumab tirumotecan

Copy Product Info
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Catalog No. T9901A-237
Synonyms SKB264, SKB 264, MK-2870, MK2870

Sacituzumab tirumotecan (SKB264) is an antibody-drug conjugate (ADC) targeting TROP2 (trophoblast cell surface antigen 2), capable of releasing the active payload KL610023 within TROP2-positive tumour cells. an effective topoisomerase I inhibitor that induces DNA damage and leads to cell cycle arrest and apoptosis, for use in non-small cell lung cancer (NSCLC) and triple-negative breast cancer (TNBC).

Sacituzumab tirumotecan
Cas No. 2768350-77-0
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$3582-4 weeks2-4 weeks
5 mg$9182-4 weeks2-4 weeks
10 mg$1,4702-4 weeks2-4 weeks
25 mg$2,8902-4 weeks2-4 weeks
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Sacituzumab tirumotecan (SKB264) is an antibody-drug conjugate (ADC) targeting TROP2 (trophoblast cell surface antigen 2), capable of releasing the active payload KL610023 within TROP2-positive tumour cells. an effective topoisomerase I inhibitor that induces DNA damage and leads to cell cycle arrest and apoptosis, for use in non-small cell lung cancer (NSCLC) and triple-negative breast cancer (TNBC).
SynonymsSKB264, SKB 264, MK-2870, MK2870
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Antigen Details
TargetTROP-2
Chemical Properties
Cas No.2768350-77-0
Storage & Solubility Information
StorageShipping with blue ice.

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