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5α-Hydroxy-6-keto cholesterol is a β-epoxide metabolite and cholesterol derivative produced in human bronchial epithelial cells (16-HBE) exposed to ozone. It inhibits cholesterol synthesis (IC50=350 nM) and exhibits cytotoxicity.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $113 | 35 days | 35 days | |
| 5 mg | $526 | 35 days | 35 days | |
| 10 mg | $997 | 35 days | 35 days |
| Description | 5α-Hydroxy-6-keto cholesterol is a β-epoxide metabolite and cholesterol derivative produced in human bronchial epithelial cells (16-HBE) exposed to ozone. It inhibits cholesterol synthesis (IC50=350 nM) and exhibits cytotoxicity. |
| In vitro | 5α-Hydroxy-6-keto cholesterol (0.01, 0.1, 1, and 10 μM) exhibits cytotoxicity to 16-HBE cells [1]. |
| Synonyms | YS64, YS 64, Yakkasterone |
| Molecular Weight | 418.66 |
| Formula | C27H46O3 |
| Cas No. | 13027-33-3 |
| Smiles | C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])(CC(=O)[C@@]1(O)C[C@@H](O)CC2)[H])[H] |
| Relative Density. | 1.061 g/cm3 (Predicted) |
| Color | White |
| Appearance | Solid |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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