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TRX-518
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Catalog No. T9901A-852
TRX-518 is a humanized agonist antibody targeting the glucocorticoid-induced tumor necrosis factor receptor (GITR). It specifically targets GITR⁺ regulatory T cells (Tregs) and CD45RA⁻Foxp3⁺ effector Tregs (eTregs) within regulatory T cells, effectively reducing the number of Tregs in circulation and within tumors.
TRX-518
TRX-518
Copy Product Info😃Good
Catalog No. T9901A-852
TRX-518 is a humanized agonist antibody targeting the glucocorticoid-induced tumor necrosis factor receptor (GITR). It specifically targets GITR⁺ regulatory T cells (Tregs) and CD45RA⁻Foxp3⁺ effector Tregs (eTregs) within regulatory T cells, effectively reducing the number of Tregs in circulation and within tumors.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Chemical Properties
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| Description | TRX-518 is a humanized agonist antibody targeting the glucocorticoid-induced tumor necrosis factor receptor (GITR). It specifically targets GITR⁺ regulatory T cells (Tregs) and CD45RA⁻Foxp3⁺ effector Tregs (eTregs) within regulatory T cells, effectively reducing the number of Tregs in circulation and within tumors. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Target | GITR |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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