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Anti-TMEFF2 Antibody
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Catalog No. T9901A-1352
Anti-TMEFF2 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human TMEFF2 protein (Tomoregulin-1) with exceptional binding affinity. It effectively facilitates the measurable detection of TMEFF2-positive malignant cells across various preclinical experimental models to evaluate the delivery of cytotoxic payloads like Auristatin E (MMAE) during strictly monitored laboratory observation periods and molecular investigations to evaluate the disruption of prostate cancer progression.
Anti-TMEFF2 Antibody
Anti-TMEFF2 Antibody
Copy Product Info🥰Excellent
Catalog No. T9901A-1352
Anti-TMEFF2 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human TMEFF2 protein (Tomoregulin-1) with exceptional binding affinity. It effectively facilitates the measurable detection of TMEFF2-positive malignant cells across various preclinical experimental models to evaluate the delivery of cytotoxic payloads like Auristatin E (MMAE) during strictly monitored laboratory observation periods and molecular investigations to evaluate the disruption of prostate cancer progression.
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| Description | Anti-TMEFF2 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human TMEFF2 protein (Tomoregulin-1) with exceptional binding affinity. It effectively facilitates the measurable detection of TMEFF2-positive malignant cells across various preclinical experimental models to evaluate the delivery of cytotoxic payloads like Auristatin E (MMAE) during strictly monitored laboratory observation periods and molecular investigations to evaluate the disruption of prostate cancer progression. |
| In vitro | In prostate cancer cell lines (LNCaP, C4-2B), Anti-TMEFF2 Antibody conjugates induced cell cycle arrest and apoptosis with IC50 values in the low nanomolar range [1]. |
| In vivo | In human prostate cancer xenograft models (LuCaP 23.1, LuCaP 35), systemic administration of Anti-TMEFF2 Antibody conjugates significantly inhibited tumor growth and led to tumor regression [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | TMEFF2 |
| Isotype | IgG1 |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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