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Citronellol-d3 ((±)-Citronelloll-d3) is the deuterium-labeled form of Citronellol. Citronellol ((±)-Citronellol) acts as an orally effective apoptosis inducer. It can prevent oxidative stress, mitochondrial dysfunction, and apoptosis in the Parkinson's disease model of SH-SY5Y cells induced by 6-OHDA through the regulation of ROS-NO, MAPK/ERK, and PI3K/Akt signaling pathways. Additionally, Citronellol induces necroptosis in human lung cancer cells via the TNF-α pathway and reactive oxygen species (ROS) accumulation. It modulates the autophagy pathway by reducing LC-3 and p62 levels, inhibiting oxidative stress and neuroinflammation, thus offering neuroprotective effects in rat models of Parkinson's disease. Furthermore, Citronellol exhibits antifungal activity against Trichophyton rubrum by inhibiting ergosterol synthesis.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
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| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | Citronellol-d3 ((±)-Citronelloll-d3) is the deuterium-labeled form of Citronellol. Citronellol ((±)-Citronellol) acts as an orally effective apoptosis inducer. It can prevent oxidative stress, mitochondrial dysfunction, and apoptosis in the Parkinson's disease model of SH-SY5Y cells induced by 6-OHDA through the regulation of ROS-NO, MAPK/ERK, and PI3K/Akt signaling pathways. Additionally, Citronellol induces necroptosis in human lung cancer cells via the TNF-α pathway and reactive oxygen species (ROS) accumulation. It modulates the autophagy pathway by reducing LC-3 and p62 levels, inhibiting oxidative stress and neuroinflammation, thus offering neuroprotective effects in rat models of Parkinson's disease. Furthermore, Citronellol exhibits antifungal activity against Trichophyton rubrum by inhibiting ergosterol synthesis. |
| Synonyms | (±)-β-Citronelloll-d3, (±)-Citronelloll-d3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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