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Cardionogen-2
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Catalog No. T204701Cas No. 578755-52-9
Cardionogen-2 is a biphasic cardiac regulatory agent that can either promote or inhibit heart formation depending on the intervention stage. It inhibits Wnt/β-catenin-dependent transcription in mouse embryonic stem cells and zebrafish embryos.
Cardionogen-2
😃Good
Catalog No. T204701Cas No. 578755-52-9
Cardionogen-2 is a biphasic cardiac regulatory agent that can either promote or inhibit heart formation depending on the intervention stage. It inhibits Wnt/β-catenin-dependent transcription in mouse embryonic stem cells and zebrafish embryos.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Cardionogen-2 is a biphasic cardiac regulatory agent that can either promote or inhibit heart formation depending on the intervention stage. It inhibits Wnt/β-catenin-dependent transcription in mouse embryonic stem cells and zebrafish embryos. |
| In vitro | Cardionogen-2 enhances cardiac formation during and after gastrulation in zebrafish embryos and mouse embryonic stem cells (ES), while it inhibits cardiac formation before gastrulation. The effects induced by Cardionogen-2 are counteracted by enhancing Wnt/β-catenin signaling activity. Cardionogen-2 suppresses Wnt/β-catenin-dependent transcription in mouse ES cells and zebrafish embryos [1]. |
| Molecular Weight | 339.372 |
| Formula | C16H13N5O2S |
| Cas No. | 578755-52-9 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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