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Dac590

Name: Dac590
Brand: TargetMol
SKU: TN11234
Price: 46 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN11234Cas No. 3084407-00-8

Alias Dac 590

Dac590 is an orally available FTO inhibitor exhibiting antiproliferative effects against AML cells, inducing apoptosis, G1 cell cycle arrest, and species growth. It is suitable for leukaemia research.

Dac590

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Purity: 98.35%

Catalog No. TN11234Alias Dac 590Cas No. 3084407-00-8

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$46	-	In Stock
5 mg	$112	-	In Stock
10 mg	$178	-	In Stock
25 mg	$357	-	In Stock
50 mg	$569	-	In Stock
100 mg	$792	-	In Stock
200 mg	$1,060	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:98.35%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Dac590 is an orally available FTO inhibitor exhibiting antiproliferative effects against AML cells, inducing apoptosis, G1 cell cycle arrest, and species growth. It is suitable for leukaemia research.
Synonyms	Dac 590

Chemical Properties

Molecular Weight	390.79
Formula	C₁₉H₁₆ClFN₂O₄
Cas No.	3084407-00-8
Smiles	O=C(O)C1=CC(OC)=CC=C1NC2=C(F)C=C(C=C2Cl)C=3C(=NOC3C)C
Relative Density.	no data available
Color	Brown
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mg/mL (25.59 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5589 mL	12.7946 mL	25.5892 mL	127.9460 mL
5 mM	0.5118 mL	2.5589 mL	5.1178 mL	25.5892 mL
10 mM	0.2559 mL	1.2795 mL	2.5589 mL	12.7946 mL
20 mM	0.1279 mL	0.6397 mL	1.2795 mL	6.3973 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc