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Benzyl salicylate (NSC 6647), a salicylic acid derivative, is protective against cisplatin-induced apoptosis in LLC-PK1 cells and also inhibits LPS-induced NO production.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 g | $29 | In Stock | |
1 mL x 10 mM (in DMSO) | $29 | In Stock |
Description | Benzyl salicylate (NSC 6647), a salicylic acid derivative, is protective against cisplatin-induced apoptosis in LLC-PK1 cells and also inhibits LPS-induced NO production. |
In vitro | In human breast cancer cell lines MCF-7 and T47D, Benzyl salicylate (10⁻⁵–10⁻⁷ M, 72 h) significantly increased cell viability, indicating estrogen-like activity. Benzyl salicylate also enhanced estrogen response element (ERE)-driven reporter gene activity and upregulated the estrogen target gene pS2, effects that were antagonized by the antiestrogen ICI 182,780[1]. |
Alias | NSC6647, NSC 6647 |
Molecular Weight | 228.24 |
Formula | C14H12O3 |
Cas No. | 118-58-1 |
Smiles | O=C(OCC=1C=CC=CC1)C=2C=CC=CC2O |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80 mg/mL (350.51 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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