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Benzyl salicylate

Name: Benzyl salicylate
Brand: TargetMol
SKU: T60290
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T60290Cas No. 118-58-1

Alias NSC6647, NSC 6647

Benzyl salicylate (NSC 6647), a salicylic acid derivative, is protective against cisplatin-induced apoptosis in LLC-PK1 cells and also inhibits LPS-induced NO production.

Benzyl salicylate

🥰Excellent

Purity: 99.86%

Catalog No. T60290Alias NSC6647, NSC 6647Cas No. 118-58-1

Benzyl salicylate (NSC 6647), a salicylic acid derivative, is protective against cisplatin-induced apoptosis in LLC-PK1 cells and also inhibits LPS-induced NO production.

Pack Size	Price	Availability	Quantity
10 g	$29	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Purity:99.86%

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Product Introduction

Bioactivity

Description	Benzyl salicylate (NSC 6647), a salicylic acid derivative, is protective against cisplatin-induced apoptosis in LLC-PK1 cells and also inhibits LPS-induced NO production.
In vitro	In human breast cancer cell lines MCF-7 and T47D, Benzyl salicylate (10⁻⁵–10⁻⁷ M, 72 h) significantly increased cell viability, indicating estrogen-like activity. Benzyl salicylate also enhanced estrogen response element (ERE)-driven reporter gene activity and upregulated the estrogen target gene pS2, effects that were antagonized by the antiestrogen ICI 182,780[1].
Synonyms	NSC6647, NSC 6647

Chemical Properties

Molecular Weight	228.24
Formula	C₁₄H₁₂O₃
Cas No.	118-58-1
Smiles	O=C(OCC=1C=CC=CC1)C=2C=CC=CC2O
Color	Transparent
Appearance	Liquid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (350.51 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (14.46 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.3814 mL	21.9068 mL	43.8135 mL	219.0676 mL
5 mM	0.8763 mL	4.3814 mL	8.7627 mL	43.8135 mL
10 mM	0.4381 mL	2.1907 mL	4.3814 mL	21.9068 mL
20 mM	0.2191 mL	1.0953 mL	2.1907 mL	10.9534 mL
50 mM	0.0876 mL	0.4381 mL	0.8763 mL	4.3814 mL
100 mM	0.0438 mL	0.2191 mL	0.4381 mL	2.1907 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc