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VU0469650 hydrochloride is a brain-penetrant negative allosteric modulator of the metabotropic glutamate receptor 1 (mGluR1). It inhibits glutamate-induced calcium flux in cells expressing human mGluR1 with an IC50 of 99 nM. VU0469650 hydrochloride holds potential for research into central nervous system disorders such as anxiety, addiction, and epilepsy.
Pack Size | Price | Availability | Quantity |
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10 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | VU0469650 hydrochloride is a brain-penetrant negative allosteric modulator of the metabotropic glutamate receptor 1 (mGluR1). It inhibits glutamate-induced calcium flux in cells expressing human mGluR1 with an IC50 of 99 nM. VU0469650 hydrochloride holds potential for research into central nervous system disorders such as anxiety, addiction, and epilepsy. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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