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T-Cadinol
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Catalog No. TN7792Cas No. 5937-11-1
Alias Cedrelanol
T-Cadinol (Cedrelanol) is a sesquiterpene compound isolated from C. sylvestris that exhibits anti-Trypanosoma cruzi activity and potential anticancer activity, inhibits trypanosomes and flagellomorphs, induces dendritic cells and drives Th1 polarization in human monocytes.T-Cadinol is a calcium antagonist that relaxes the contraction of 60 mM K+ induced by T-Cadinol in a concentration-dependent manner. 60 mM K+-induced contraction.
T-Cadinol
😃Good
Catalog No. TN7792Alias CedrelanolCas No. 5937-11-1
T-Cadinol (Cedrelanol) is a sesquiterpene compound isolated from C. sylvestris that exhibits anti-Trypanosoma cruzi activity and potential anticancer activity, inhibits trypanosomes and flagellomorphs, induces dendritic cells and drives Th1 polarization in human monocytes.T-Cadinol is a calcium antagonist that relaxes the contraction of 60 mM K+ induced by T-Cadinol in a concentration-dependent manner. 60 mM K+-induced contraction.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $575 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | T-Cadinol (Cedrelanol) is a sesquiterpene compound isolated from C. sylvestris that exhibits anti-Trypanosoma cruzi activity and potential anticancer activity, inhibits trypanosomes and flagellomorphs, induces dendritic cells and drives Th1 polarization in human monocytes.T-Cadinol is a calcium antagonist that relaxes the contraction of 60 mM K+ induced by T-Cadinol in a concentration-dependent manner. 60 mM K+-induced contraction. |
| Targets&IC50 | T. cruzi (no-flagellate):15.8 μM, T. cruzi (trypanosome):18.2 μM |
| In vitro | T-Cadinol, a sesquiterpenoid derived from C. sylvestris, exhibited antitrypanosomal effects against Trypanosoma cruzi, with IC50 of 18.2 μM and 15.8 μM for trypanosome and no-flagellate, respectively. [1] |
| Synonyms | Cedrelanol |
| Molecular Weight | 222.37 |
| Formula | C15H26O |
| Cas No. | 5937-11-1 |
| Smiles | [C@@H](C)(C)[C@H]1[C@]2([C@]([C@@](C)(O)CC1)(CCC(C)=C2)[H])[H] |
| Storage | keep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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