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T-Cadinol

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Catalog No. TN7792Cas No. 5937-11-1
Alias Cedrelanol

T-Cadinol (Cedrelanol) is a sesquiterpene compound isolated from C. sylvestris that exhibits anti-Trypanosoma cruzi activity and potential anticancer activity, inhibits trypanosomes and flagellomorphs, induces dendritic cells and drives Th1 polarization in human monocytes.T-Cadinol is a calcium antagonist that relaxes the contraction of 60 mM K+ induced by T-Cadinol in a concentration-dependent manner. 60 mM K+-induced contraction.

T-Cadinol

T-Cadinol

😃Good
Catalog No. TN7792Alias CedrelanolCas No. 5937-11-1
T-Cadinol (Cedrelanol) is a sesquiterpene compound isolated from C. sylvestris that exhibits anti-Trypanosoma cruzi activity and potential anticancer activity, inhibits trypanosomes and flagellomorphs, induces dendritic cells and drives Th1 polarization in human monocytes.T-Cadinol is a calcium antagonist that relaxes the contraction of 60 mM K+ induced by T-Cadinol in a concentration-dependent manner. 60 mM K+-induced contraction.
Pack SizePriceAvailabilityQuantity
1 mg$940In Stock
5 mg$2,4007-10 days
10 mg$3,6007-10 days
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Product Introduction

Bioactivity
Description
T-Cadinol (Cedrelanol) is a sesquiterpene compound isolated from C. sylvestris that exhibits anti-Trypanosoma cruzi activity and potential anticancer activity, inhibits trypanosomes and flagellomorphs, induces dendritic cells and drives Th1 polarization in human monocytes.T-Cadinol is a calcium antagonist that relaxes the contraction of 60 mM K+ induced by T-Cadinol in a concentration-dependent manner. 60 mM K+-induced contraction.
Targets&IC50
T. cruzi (trypanosome):18.2 μM, T. cruzi (no-flagellate):15.8 μM
In vitro
T-Cadinol, a sesquiterpenoid derived from C. sylvestris, exhibited antitrypanosomal effects against Trypanosoma cruzi, with IC50 of 18.2 μM and 15.8 μM for trypanosome and no-flagellate, respectively. [1]
SynonymsCedrelanol
Chemical Properties
Molecular Weight222.37
FormulaC15H26O
Cas No.5937-11-1
Smiles[C@@H](C)(C)[C@H]1[C@]2([C@]([C@@](C)(O)CC1)(CCC(C)=C2)[H])[H]
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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