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11-Oxomogroside IIIE is a cucurbitane triterpene glycoside isolated from Siraitia grosvenorii (Lo Han Kuo), a traditional Chinese fruit used as a pulmonary demulcent for conditions including dry cough, sore throat, thirst, and constipation. Triterpenoids from this plant were evaluated for inhibition of Epstein–Barr virus early antigen induction by TPA in Raji cells, a primary screen for antitumor promoters, amongst all tested compounds, 11-Oxomogroside IIIE exhibited strong suppression with 70–100% inhibition at 1 × 10³ mol ratio/TPA.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $139 | - | In Stock | |
| 5 mg | $372 | - | In Stock | |
| 10 mg | $579 | - | In Stock | |
| 25 mg | $891 | - | In Stock | |
| 50 mg | $1,220 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $612 | - | In Stock |
| Description | 11-Oxomogroside IIIE is a cucurbitane triterpene glycoside isolated from Siraitia grosvenorii (Lo Han Kuo), a traditional Chinese fruit used as a pulmonary demulcent for conditions including dry cough, sore throat, thirst, and constipation. Triterpenoids from this plant were evaluated for inhibition of Epstein–Barr virus early antigen induction by TPA in Raji cells, a primary screen for antitumor promoters, amongst all tested compounds, 11-Oxomogroside IIIE exhibited strong suppression with 70–100% inhibition at 1 × 10³ mol ratio/TPA. |
| Molecular Weight | 961.14 |
| Formula | C48H80O19 |
| Cas No. | 2096516-68-4 |
| Smiles | C[C@]12[C@]([C@@]3(C)[C@](C)(CC1=O)[C@@]([C@@H](CC[C@@H](O[C@H]4[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@@H](CO)O4)C(C)(C)O)C)(CC3)[H])(CC=C6[C@]2(CC[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)C6(C)C)[H])[H] |
| Relative Density. | 1.40 g/cm3 (Predicted) |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (83.23 mM), Sonication is recommeded. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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