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Anti-CDH6/K-Cadherin Antibody
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Catalog No. T9901A-823
Alias HKT288 antibody
Anti-CDH6/K-Cadherin Antibody is a highly specialized monoclonal antibody target the human cadherin-6 protein, which is a type II classical cadherin primarily expressed in the kidney and various malignant tissues, inhibition of calcium-dependent cell-cell adhesion across various preclinical experimental models to modulate tumor cell invasion and metastatic potential.
Anti-CDH6/K-Cadherin Antibody
Anti-CDH6/K-Cadherin Antibody
Copy Product Info😃Good
Catalog No. T9901A-823Alias HKT288 antibody
Anti-CDH6/K-Cadherin Antibody is a highly specialized monoclonal antibody target the human cadherin-6 protein, which is a type II classical cadherin primarily expressed in the kidney and various malignant tissues, inhibition of calcium-dependent cell-cell adhesion across various preclinical experimental models to modulate tumor cell invasion and metastatic potential.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-CDH6/K-Cadherin Antibody is a highly specialized monoclonal antibody target the human cadherin-6 protein, which is a type II classical cadherin primarily expressed in the kidney and various malignant tissues, inhibition of calcium-dependent cell-cell adhesion across various preclinical experimental models to modulate tumor cell invasion and metastatic potential. |
| In vitro | In cell-based cytotoxicity assays using OVCAR-3 ovarian cancer cells, Anti-CDH6/K-Cadherin Antibody (HKT288 ADC) demonstrated potent antigen-specific killing with IC50 values in the low nanomolar range [1]. |
| In vivo | In human ovarian and renal cancer xenograft models, systemic administration of Anti-CDH6/K-Cadherin Antibody (HKT288 ADC) resulted in significant tumor regression and durable antitumor responses [1]. |
| Synonyms | HKT288 antibody |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | CDH6/K-Cadherin |
| Isotype | IgG1 |
| Storage | store at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice. |
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