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Anti-CDH6/K-Cadherin Antibody
(Synonyms: HKT288 antibody) Copy Product Info
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Synonyms: HKT288 antibody
Catalog No. T9901A-823 Copy Product Info
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Anti-CDH6/K-Cadherin Antibody is a highly specialized monoclonal antibody target the human cadherin-6 protein, which is a type II classical cadherin primarily expressed in the kidney and various malignant tissues, inhibition of calcium-dependent cell-cell adhesion across various preclinical experimental models to modulate tumor cell invasion and metastatic potential.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-CDH6/K-Cadherin Antibody is a highly specialized monoclonal antibody target the human cadherin-6 protein, which is a type II classical cadherin primarily expressed in the kidney and various malignant tissues, inhibition of calcium-dependent cell-cell adhesion across various preclinical experimental models to modulate tumor cell invasion and metastatic potential. |
| In vitro | In cell-based cytotoxicity assays using OVCAR-3 ovarian cancer cells, Anti-CDH6/K-Cadherin Antibody (HKT288 ADC) demonstrated potent antigen-specific killing with IC50 values in the low nanomolar range [1]. |
| In vivo | In human ovarian and renal cancer xenograft models, systemic administration of Anti-CDH6/K-Cadherin Antibody (HKT288 ADC) resulted in significant tumor regression and durable antitumor responses [1]. |
| Synonyms | HKT288 antibody |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | CDH6/K-Cadherin |
| Isotype | IgG1 |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Anti-CDH6/K-Cadherin Antibody chemical structure | Anti-CDH6/K-Cadherin Antibody in vivo | Anti-CDH6/K-Cadherin Antibody in vitro
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