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UNC10142

Name: UNC10142
Brand: TargetMol
SKU: T203332
Rating: 4.5 (1 reviews)

(Synonyms: UNC-10142, UNC 10142) Copy Product Info

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Synonyms: UNC-10142, UNC 10142

Catalog No. T203332 Copy Product Info

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UNC10142 is a small-molecule antagonist of CHD1 (IC₅₀ = 1.7 μM). UNC10142 induces dose-dependent reduction in the viability of PTEN-deficient prostate cancer cells.

Cas No. 3118919-69-7

Pack Size	Price	USA Stock	Global Stock	Quantity
10 mg	Inquiry	Inquiry	Inquiry
50 mg	Inquiry	Inquiry	Inquiry

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Appearance:Solid

Color:Yellow

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COA

Product Introduction

Bioactivity

Description	UNC10142 is a small-molecule antagonist of CHD1 (IC₅₀ = 1.7 μM). UNC10142 induces dose-dependent reduction in the viability of PTEN-deficient prostate cancer cells.
Targets & IC50	CHD1:1.7 μM
Synonyms	UNC-10142, UNC 10142

Chemical Properties

Molecular Weight	580.80
Formula	C₃₃H₅₂N₆O₃
Cas No.	3118919-69-7
Smiles	COC1=CC2=C(N=C(N3CCCCCCCC3)N=C2N(C)C4CCN(C(C)=O)CC4)C=C1OCCCN5CCCCC5

Storage & Solubility Information

Storage

Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80.00 mg/mL (137.74 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7218 mL	8.6088 mL	17.2176 mL	86.0882 mL
5 mM	0.3444 mL	1.7218 mL	3.4435 mL	17.2176 mL
10 mM	0.1722 mL	0.8609 mL	1.7218 mL	8.6088 mL
20 mM	0.0861 mL	0.4304 mL	0.8609 mL	4.3044 mL
50 mM	0.0344 mL	0.1722 mL	0.3444 mL	1.7218 mL
100 mM	0.0172 mL	0.0861 mL	0.1722 mL	0.8609 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.