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Synonyms: Qdm, Qa-1b, MHC, H2-T23


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $87 | 7-10 days | 7-10 days | |
| 10 µg | $133 | 7-10 days | 7-10 days | |
| 20 µg | $198 | 7-10 days | 7-10 days | |
| 50 µg | $377 | 7-10 days | 7-10 days | |
| 100 µg | $598 | 7-10 days | 7-10 days | |
| 200 µg | $948 | 7-10 days | 7-10 days | |
| 500 µg | $1,760 | 7-10 days | 7-10 days |
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. |
| Description | Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein, Mouse, MHC (His & Avi), Biotinylated is expressed in HEK293 Cells. The accession number is P06339(Q1-1b)&P01887(B2M)&AMAPRTLLL. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | C-His-Avi |
| Accession Number | P06339(Q1-1b)&P01887(B2M)&AMAPRTLLL |
| Construction | His23-Pro296 (Qa-1b), Ile21-Met119 (B2M) and AMAPRTLLL peptide |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | Qdm, Qa-1b, MHC, H2-T23 |
| Research Background | Qa-1b binds a peptide (AMAPRTLLL), referred to as Qdm (for Qa-1 determinant modifier), derived from the signal sequence of murine class Ia molecules. This peptide binds with high affinity and accounts for almost all of the peptides associated with this molecule. Human histocompatibility leukocyte antigen (HLA)-E, a homologue of Qa-1b, binds similar peptides derived from human class Ia molecules and interacts with CD94/NKG2 receptors on natural killer cells. |
| Molecular Weight | 50.60 kDa (Predicted); 55-65 kDa (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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