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Gentiakochianin (Swertianine), an anthrone from Gentianaceae, has vasodilatory activity, induces glioma cell cycle arrest in the G(2)/M phase and inhibits proliferation, significantly reduces oxLDL-induced cell damage in EA.hy926 cells, inhibits ROS levels and up-regulated the activity of Akt/CREB/eNOS signaling pathway inhibited by oxLDL.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $65 | In Stock | |
| 5 mg | $150 | In Stock | |
| 10 mg | $218 | In Stock | |
| 25 mg | $369 | In Stock |
| Description | Gentiakochianin (Swertianine), an anthrone from Gentianaceae, has vasodilatory activity, induces glioma cell cycle arrest in the G(2)/M phase and inhibits proliferation, significantly reduces oxLDL-induced cell damage in EA.hy926 cells, inhibits ROS levels and up-regulated the activity of Akt/CREB/eNOS signaling pathway inhibited by oxLDL. |
| Synonyms | Swertianin, NSC 289490 |
| Molecular Weight | 274.23 |
| Formula | C14H10O6 |
| Cas No. | 20882-75-1 |
| Smiles | O=C1C2=C(O)C=C(OC)C=C2OC3=CC=C(O)C(O)=C13 |
| Relative Density. | 1.586 g/cm3 |
| Color | Yellow |
| Appearance | Solid |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||
| Solubility Information | DMSO: 1 mg/mL (3.65 mM), Sonication and heating are recommended. | ||||||||||
Solution Preparation Table | |||||||||||
DMSO
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