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Gentiakochianin
🥰Excellent
Catalog No. T19932Cas No. 20882-75-1
Alias Swertianin, NSC 289490
Gentiakochianin (Swertianine), an anthrone from Gentianaceae, has vasodilatory activity, induces glioma cell cycle arrest in the G(2)/M phase and inhibits proliferation, significantly reduces oxLDL-induced cell damage in EA.hy926 cells, inhibits ROS levels and up-regulated the activity of Akt/CREB/eNOS signaling pathway inhibited by oxLDL.
Gentiakochianin
🥰Excellent
Purity: 98.97%
Catalog No. T19932Alias Swertianin, NSC 289490Cas No. 20882-75-1
Gentiakochianin (Swertianine), an anthrone from Gentianaceae, has vasodilatory activity, induces glioma cell cycle arrest in the G(2)/M phase and inhibits proliferation, significantly reduces oxLDL-induced cell damage in EA.hy926 cells, inhibits ROS levels and up-regulated the activity of Akt/CREB/eNOS signaling pathway inhibited by oxLDL.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $65 | In Stock | |
| 5 mg | $150 | In Stock | |
| 10 mg | $218 | In Stock | |
| 25 mg | $369 | In Stock |
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Purity:98.97%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Gentiakochianin (Swertianine), an anthrone from Gentianaceae, has vasodilatory activity, induces glioma cell cycle arrest in the G(2)/M phase and inhibits proliferation, significantly reduces oxLDL-induced cell damage in EA.hy926 cells, inhibits ROS levels and up-regulated the activity of Akt/CREB/eNOS signaling pathway inhibited by oxLDL. |
| Alias | Swertianin, NSC 289490 |
| Molecular Weight | 274.23 |
| Formula | C14H10O6 |
| Cas No. | 20882-75-1 |
| Smiles | O=C1C2=C(O)C=C(OC)C=C2OC3=CC=C(O)C(O)=C13 |
| Relative Density. | 1.586 g/cm3 |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
| Solubility Information | DMSO: 1 mg/mL (3.65 mM), Sonication and heating are recommended. | ||||||||||
Solution Preparation Table | |||||||||||
DMSO
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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