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R707
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Catalog No. T9901A-1237
R707 is a humanized monoclonal antibody expressed in CHO cells targeting C-C chemokine receptor type 7 (CCR7/CD197). This product, featuring a huIgG1 heavy chain and a hukappa light chain, has a predicted molecular weight of 145.36 kDa. R707 specifically binds to CCR7, blocking its interaction with ligands CCL19 and CCL21. This blockade inhibits CCR7-mediated cell migration, chemotaxis, and lymphocyte homing to lymph nodes. It exhibits significant biological activity in researching chronic lymphocytic leukemia (CLL), autoimmune diseases, and lymph node metastasis of tumor cells.
R707
R707
Copy Product Info🥰Excellent
Catalog No. T9901A-1237
R707 is a humanized monoclonal antibody expressed in CHO cells targeting C-C chemokine receptor type 7 (CCR7/CD197). This product, featuring a huIgG1 heavy chain and a hukappa light chain, has a predicted molecular weight of 145.36 kDa. R707 specifically binds to CCR7, blocking its interaction with ligands CCL19 and CCL21. This blockade inhibits CCR7-mediated cell migration, chemotaxis, and lymphocyte homing to lymph nodes. It exhibits significant biological activity in researching chronic lymphocytic leukemia (CLL), autoimmune diseases, and lymph node metastasis of tumor cells.
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| Description | R707 is a humanized monoclonal antibody expressed in CHO cells targeting C-C chemokine receptor type 7 (CCR7/CD197). This product, featuring a huIgG1 heavy chain and a hukappa light chain, has a predicted molecular weight of 145.36 kDa. R707 specifically binds to CCR7, blocking its interaction with ligands CCL19 and CCL21. This blockade inhibits CCR7-mediated cell migration, chemotaxis, and lymphocyte homing to lymph nodes. It exhibits significant biological activity in researching chronic lymphocytic leukemia (CLL), autoimmune diseases, and lymph node metastasis of tumor cells. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | CCR7/CD197 |
| Isotype | IgG1 |
| Storage | store at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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