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Anti-Mouse OX40/CD134 Antibody (OX-86)
(Synonyms: OX86) Copy Product Info
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Synonyms: OX86
Catalog No. T9901A-617 Copy Product Info
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Anti-Mouse OX40/CD134 Antibody (OX-86) is a monoclonal inhibitory antibody targeting mouse OX40/CD134. It can enhance the anti-tumor effect of CD8+ T cells, reverse the immunosuppressive microenvironment, promote antigen presentation and T cell activation, and is applicable to tumor-related studies such as papilloma and leukemia.
Anti-Mouse OX40/CD134 Antibody
(OX-86)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $126 | 2-4 weeks | 2-4 weeks | |
| 5 mg | $382 | 2-4 weeks | 2-4 weeks | |
| 10 mg | Preferential | 2-4 weeks | 2-4 weeks |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Mouse OX40/CD134 Antibody (OX-86) is a monoclonal inhibitory antibody targeting mouse OX40/CD134. It can enhance the anti-tumor effect of CD8+ T cells, reverse the immunosuppressive microenvironment, promote antigen presentation and T cell activation, and is applicable to tumor-related studies such as papilloma and leukemia. |
| In vitro | Anti-Mouse OX40/CD134 Antibody (OX-86) upregulates the expression of surface activation markers CD40 and CD86 on dendritic cells (DCs) and downregulates PD-L1 levels in SB28‑OVA and EG7‑OVA cells when treated at 100 µg/mL for 5–7 days [3]. Anti-Mouse OX40/CD134 Antibody (OX-86) pretreatment at 10 µg/mL for 1 hour significantly enhances tumor cell apoptosis mediated by tumor-infiltrating lymphocytes (TILs) [4]. |
| In vivo | Anti-Mouse OX40/CD134 Antibody (OX-86) administered intraperitoneally at 100 µg twice weekly shows only limited antitumor efficacy in female C57BL/6 mice bearing TC-1 tumors [1]. Anti-Mouse OX40/CD134 Antibody (OX-86) administered intraperitoneally at 10 mg/kg once weekly for 2 doses, in combination with PEG-MTAP, significantly inhibits tumor growth in DBA/2 mice bearing L1210 tumors [2]. Anti-Mouse OX40/CD134 Antibody (OX-86) administered intraperitoneally at 200 µg on days 4, 7, and 10 significantly inhibits tumor growth in female C57BL/6 mice bearing SB28-OVA or EG7-OVA tumors [3]. Anti-Mouse OX40/CD134 Antibody (OX-86) administered intraperitoneally at 100 µg twice weekly for 2 weeks delays tumor growth and enhances CD8+ T cell function in C57BL/6 mice bearing MC38 tumors [4]. |
| Synonyms | OX86 |
| Clone | OX-86 |
| Reactivity | Mouse |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TNFRSF4/OX40/CD134 |
| Molecular Weight | 150 kDa |
| Isotype | Rat IgG1 |
| Recommended Isotype Control |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Anti-Mouse OX40/CD134 Antibody (OX-86) in vivo | Anti-Mouse OX40/CD134 Antibody (OX-86) in vitro | Anti-Mouse OX40/CD134 Antibody (OX-86) molecular weight
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