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Anti-TREML2 Antibody (3V949)
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Catalog No. TMAY-01964
Alias UNQ6268/PRO20473, triggering receptor expressed on myeloid cells like 2, TLT-2, TLT2, MGC149716, MGC149715, FLJ13693, dJ238O23.1, C6orf76
Anti-TREML2 Antibody (3V949) is a Rabbit antibody targeting TREML2. Anti-TREML2 Antibody (3V949) can be used in ELISA.
Anti-TREML2 Antibody (3V949)
Anti-TREML2 Antibody (3V949)
😃Good
Catalog No. TMAY-01964Alias UNQ6268/PRO20473, triggering receptor expressed on myeloid cells like 2, TLT-2, TLT2, MGC149716, MGC149715, FLJ13693, dJ238O23.1, C6orf76
Anti-TREML2 Antibody (3V949) is a Rabbit antibody targeting TREML2. Anti-TREML2 Antibody (3V949) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Chemical Properties
| Description | Anti-TREML2 Antibody (3V949) is a Rabbit antibody targeting TREML2. Anti-TREML2 Antibody (3V949) can be used in ELISA. |
| Synonyms | UNQ6268/PRO20473, triggering receptor expressed on myeloid cells like 2, TLT-2, TLT2, MGC149716, MGC149715, FLJ13693, dJ238O23.1, C6orf76 |
| Ig Type | Rabbit IgG |
| Clone | 3V949 |
| Reactivity | Human |
| Specificity | Human TLT-2/TREML2 No cross-reactivity in ELISA with Human TREML1 |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human TREML2 / TLT-2 (rh TREML2 / TLT-2; TMPY-01648; NP_079083.2; Met1-Ser268). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like) domain. TREML2 is detected in cultured B cells, T cell leukemia and monocyte leukemia. TREML2 is expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation. TREML2 is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML2 acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation. Murine B7-H3 is specifically bound to Triggering receptor expressed on myeloid cells (TREM)-like transcript 2 (TLT-2, TREML2). TREML2 was expressed on CD8(+) T cells constitutively and on activated CD4(+) T cells. Stimulation with B7-H3 transfectants preferentially up-regulated the proliferation and IFN-gamma production of CD8(+) T cells. Transduction of TREML2 into T cells resulted in enhanced IL-2 and IFN-gamma production via interactions with B7-H3. There may be a direct interaction between B7-H3 and TREML2 that preferentially enhances CD8(+) T cell activation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human TREML2 / TLT-2 protein (TMPY-01648) |
| Antigen Species | Human |
| Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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