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Sabatolimab

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Catalog No. T76699Cas No. 2252262-24-9
Alias NVP-MBG453, MBG453

Sabatolimab (MBG453), a humanized IgG4 (S228P) antibody targeting TIM-3, is a potent inhibitory receptor that regulates adaptive and innate immune responses. Sabatolimab has potential immunosuppressive activity and selectively binds to TIM-3 on immune cells and bone marrow cells.

Sabatolimab

Sabatolimab

😃Good
Catalog No. T76699Alias NVP-MBG453, MBG453Cas No. 2252262-24-9
Sabatolimab (MBG453), a humanized IgG4 (S228P) antibody targeting TIM-3, is a potent inhibitory receptor that regulates adaptive and innate immune responses. Sabatolimab has potential immunosuppressive activity and selectively binds to TIM-3 on immune cells and bone marrow cells.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$178In StockIn Stock
5 mg$538In StockIn Stock
10 mg$913-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:> 95%
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Product Introduction

Bioactivity
Description
Sabatolimab (MBG453), a humanized IgG4 (S228P) antibody targeting TIM-3, is a potent inhibitory receptor that regulates adaptive and innate immune responses. Sabatolimab has potential immunosuppressive activity and selectively binds to TIM-3 on immune cells and bone marrow cells.
SynonymsNVP-MBG453, MBG453
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetTIM-3/HAVCR2/CD366
Chemical Properties
Molecular Weight146.1 kDa
Cas No.2252262-24-9
ColorTransparent
AppearanceLiquid
Antibody Information
IsotypeHuman IgG4SP kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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