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Dehydroergosterol

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Catalog No. T37858Cas No. 516-85-8
Alias 9,11-dehydro Ergosterol

Dehydroergosterol (DHE) is a naturally occurring fluorescent sterol analog that is a compound for real-time detection/elaboration of the sterol environment and intracellular sterol transport in organisms. Dehydroergosterol is a cholesterol mimetic that binds to cholesterol-binding proteins and can be used for real-time imaging of living cells. Dehydroergosterol is a cholesterol mimetic that binds to cholesterol-binding proteins and can be used for real-time imaging of living cells.

Dehydroergosterol

Dehydroergosterol

😃Good
Catalog No. T37858Alias 9,11-dehydro ErgosterolCas No. 516-85-8
Dehydroergosterol (DHE) is a naturally occurring fluorescent sterol analog that is a compound for real-time detection/elaboration of the sterol environment and intracellular sterol transport in organisms. Dehydroergosterol is a cholesterol mimetic that binds to cholesterol-binding proteins and can be used for real-time imaging of living cells. Dehydroergosterol is a cholesterol mimetic that binds to cholesterol-binding proteins and can be used for real-time imaging of living cells.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$12035 days35 days
5 mg$34835 days35 days
10 mg$63835 days35 days
25 mg$1,43035 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Appearance:Solid
Color:White to Yellow
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Product Introduction

Bioactivity
Description
Dehydroergosterol (DHE) is a naturally occurring fluorescent sterol analog that is a compound for real-time detection/elaboration of the sterol environment and intracellular sterol transport in organisms. Dehydroergosterol is a cholesterol mimetic that binds to cholesterol-binding proteins and can be used for real-time imaging of living cells. Dehydroergosterol is a cholesterol mimetic that binds to cholesterol-binding proteins and can be used for real-time imaging of living cells.
Synonyms9,11-dehydro Ergosterol
Chemical Properties
Molecular Weight394.63
FormulaC28H42O
Cas No.516-85-8
SmilesC[C@@]12[C@](C=3C([C@]4(C)C(=CC3)C[C@@H](O)CC4)=CC1)(CC[C@@]2([C@@H](/C=C/[C@@H](C(C)C)C)C)[H])[H]
Storage & Solubility Information
Storagekeep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMF: 1 mg/mL (2.53 mM), Sonication is recommended.
Ethanol: 10 mg/mL (25.34 mM), Sonication is recommended.
DMSO: < 1 mg/mL (insoluble)
Solution Preparation Table
DMF/Ethanol
1mg5mg10mg50mg
1 mM2.5340 mL12.6701 mL25.3402 mL126.7010 mL
Ethanol
1mg5mg10mg50mg
5 mM0.5068 mL2.5340 mL5.0680 mL25.3402 mL
10 mM0.2534 mL1.2670 mL2.5340 mL12.6701 mL
20 mM0.1267 mL0.6335 mL1.2670 mL6.3350 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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