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Halobetasol propionate (Standard)

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Catalog No. TMSM-1295Cas No. 66852-54-8
Alias Halobetasol propionate (Standard)

Halobetasol propionate (Standard) is the standard substance of Halobetasol propionate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Halobetasol propionate (BMY-30056) is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities. Halobetasol, a topical steroid, diffuses across cell membranes to interact with cytoplasmic corticosteroid receptors located in both the dermal and intradermal cells, thereby activating gene expression of anti-inflammatory proteins mediated via corticosteroid receptor response element. Specifically, this agent induces phospholipase A2 inhibitory proteins, which inhibit the release of arachidonic acid, thereby inhibiting the biosynthesis of potent mediators of inflammation, such as prostaglandins and leukotrienes. As a result, halobetasol reduces edema, erythema, and pruritus through its cutaneous effects on vascular dilation and permeability.

Halobetasol  propionate (Standard)

Halobetasol propionate (Standard)

😃Good
Catalog No. TMSM-1295Alias Halobetasol propionate (Standard)Cas No. 66852-54-8
Halobetasol propionate (Standard) is the standard substance of Halobetasol propionate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Halobetasol propionate (BMY-30056) is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities. Halobetasol, a topical steroid, diffuses across cell membranes to interact with cytoplasmic corticosteroid receptors located in both the dermal and intradermal cells, thereby activating gene expression of anti-inflammatory proteins mediated via corticosteroid receptor response element. Specifically, this agent induces phospholipase A2 inhibitory proteins, which inhibit the release of arachidonic acid, thereby inhibiting the biosynthesis of potent mediators of inflammation, such as prostaglandins and leukotrienes. As a result, halobetasol reduces edema, erythema, and pruritus through its cutaneous effects on vascular dilation and permeability.
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Description
Halobetasol propionate (Standard) is the standard substance of Halobetasol propionate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Halobetasol propionate (BMY-30056) is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities. Halobetasol, a topical steroid, diffuses across cell membranes to interact with cytoplasmic corticosteroid receptors located in both the dermal and intradermal cells, thereby activating gene expression of anti-inflammatory proteins mediated via corticosteroid receptor response element. Specifically, this agent induces phospholipase A2 inhibitory proteins, which inhibit the release of arachidonic acid, thereby inhibiting the biosynthesis of potent mediators of inflammation, such as prostaglandins and leukotrienes. As a result, halobetasol reduces edema, erythema, and pruritus through its cutaneous effects on vascular dilation and permeability.
SynonymsHalobetasol propionate (Standard)
Chemical Properties
Molecular Weight484.96
FormulaC25H31ClF2O5
Cas No.66852-54-8
Relative Density.1.31 g/cm3
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