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Anticancer agent 221
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Catalog No. T210028
Anticanceragent 221 (Compound 4h) is an orally active anticancer and antioxidant agent. It exhibits cytotoxicity against cancer cells A549 (IC50=22.09 µg/mL) and MCF-7 (IC50=6.40 µg/mL) and induces apoptosis. It demonstrates antioxidant activity with an IC50 of 42.46 μM in the DPPH assay. In mouse models, Anticanceragent 221 shows antitumor efficacy against breast cancer.
Anticancer agent 221
Anticancer agent 221
🥰Excellent
Catalog No. T210028
Anticanceragent 221 (Compound 4h) is an orally active anticancer and antioxidant agent. It exhibits cytotoxicity against cancer cells A549 (IC50=22.09 µg/mL) and MCF-7 (IC50=6.40 µg/mL) and induces apoptosis. It demonstrates antioxidant activity with an IC50 of 42.46 μM in the DPPH assay. In mouse models, Anticanceragent 221 shows antitumor efficacy against breast cancer.
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Product Introduction
Bioactivity
Chemical Properties
| Description | Anticanceragent 221 (Compound 4h) is an orally active anticancer and antioxidant agent. It exhibits cytotoxicity against cancer cells A549 (IC50=22.09 µg/mL) and MCF-7 (IC50=6.40 µg/mL) and induces apoptosis. It demonstrates antioxidant activity with an IC50 of 42.46 μM in the DPPH assay. In mouse models, Anticanceragent 221 shows antitumor efficacy against breast cancer. |
| Formula | C17H9F4NO3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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