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4-Chlorochalcone

Name: 4-Chlorochalcone
Brand: TargetMol
SKU: T205870
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T205870Cas No. 956-04-7

4-Chlorochalcone is a biologically active chalcone with potential inhibitory effects on human MAO-B and ROS/RNS production and is able to inhibit the growth of CAL51 cells.

4-Chlorochalcone

🥰Excellent

Purity: 98.08%

Catalog No. T205870Cas No. 956-04-7

4-Chlorochalcone is a biologically active chalcone with potential inhibitory effects on human MAO-B and ROS/RNS production and is able to inhibit the growth of CAL51 cells.

Pack Size	Price	Availability
100 mg	$30	In Stock
500 mg	$55	In Stock
1 g	$83	In Stock

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Purity:98.08%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	4-Chlorochalcone is a biologically active chalcone with potential inhibitory effects on human MAO-B and ROS/RNS production and is able to inhibit the growth of CAL51 cells.
Targets&IC50	MAO-A:9.10 ± 0.038 μM, AChE:1.25 ± 0.42 μM, MAO-B:0.066 ± 0.0025 μM
In vitro	4-Chlorochalcone strongly inhibits MAO-A (IC₅₀ = 9.10 ± 0.038 μM) and MAO-B (IC₅₀ = 0.066 ± 0.0025 μM) in vitro, with slight MAO-B selectivity. 4-Chlorochalcone weakly inhibits AChE (IC₅₀ = 1.25 ± 0.42μM)[1].

Chemical Properties

Molecular Weight	242.7
Formula	C₁₅H₁₁ClO
Cas No.	956-04-7
Smiles	O=C(C=CC1=CC=C(Cl)C=C1)C=2C=CC=CC2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

H2O: < 1 mg/mL (insoluble)

DMSO: 100 mg/mL (412.03 mM), Sonication and heating are recommended.

Ethanol: 1 mg/mL (4.12 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	4.1203 mL	20.6016 mL	41.2031 mL	206.0157 mL

DMSO

	1mg	5mg	10mg	50mg
5 mM	0.8241 mL	4.1203 mL	8.2406 mL	41.2031 mL
10 mM	0.4120 mL	2.0602 mL	4.1203 mL	20.6016 mL
20 mM	0.2060 mL	1.0301 mL	2.0602 mL	10.3008 mL
50 mM	0.0824 mL	0.4120 mL	0.8241 mL	4.1203 mL
100 mM	0.0412 mL	0.2060 mL	0.4120 mL	2.0602 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc