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Synonyms: survivin variant 3 alpha, Survivin, MHC I, MHC, IAP4, EPR-1, BIRC5, API4


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $147 | 7-10 days | 7-10 days | |
| 20 µg | $228 | 7-10 days | 7-10 days | |
| 50 µg | $419 | 7-10 days | 7-10 days | |
| 100 µg | $665 | 7-10 days | 7-10 days | |
| 200 µg | $1,050 | 7-10 days | 7-10 days | |
| 500 µg | $1,960 | 7-10 days | 7-10 days |
| Bioactivity | Immobilized Biotinylated Human HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Monomer, His Tag at 1 μg/ml (100 μl/well) on the streptavidin precoated plate (5 μg/ml). Dose response curve for Anti-B2M Antibody, mFc Tag with the EC50 of 10.9 ng/ml determined by ELISA (QC Test). |
| Description | HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated is expressed in HEK293 Cells. The accession number is A0A140T913(HLA-A*02:01)&P61769(B2M)<LGEFLKL. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His-Avi |
| Accession Number | A0A140T913(HLA-A*02:01)&P61769(B2M)<LGEFLKL |
| Construction | Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and LTLGEFLKL peptide |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| Synonyms | survivin variant 3 alpha, Survivin, MHC I, MHC, IAP4, EPR-1, BIRC5, API4 |
| Research Background | Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers; consequently, it has received significant attention as a potential oncotherapeutic target. |
| Molecular Weight | 50.44 kDa (Predicted); 52-65 kDa (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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