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APX-007
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Catalog No. T9901A-1471 Copy Product Info
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APX-007 is a human monoclonal antibody expressed in CHO cells that specifically targets IL-6 Receptor alpha (IL-6Rα/CD126). It features a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight of approximately 150 kDa. By binding to IL-6Rα, APX-007 blocks the interaction between IL-6 and its receptor, thereby inhibiting both classical and trans-signaling pathways mediated by IL-6 and suppressing downstream inflammatory cascades. This antibody is a valuable tool for research into autoimmune diseases and chronic inflammation. The recommended isotype control is Human IgG1 kappa, Isotype Control (HY-P99001).
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $377 | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Antibody Information
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| Description | APX-007 is a human monoclonal antibody expressed in CHO cells that specifically targets IL-6 Receptor alpha (IL-6Rα/CD126). It features a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight of approximately 150 kDa. By binding to IL-6Rα, APX-007 blocks the interaction between IL-6 and its receptor, thereby inhibiting both classical and trans-signaling pathways mediated by IL-6 and suppressing downstream inflammatory cascades. This antibody is a valuable tool for research into autoimmune diseases and chronic inflammation. The recommended isotype control is Human IgG1 kappa, Isotype Control (HY-P99001). |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | IL-6Ra/CD126 |
| Isotype | IgG1 |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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