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Afimkibart (Synonyms: RVT-3101, RVT3101, PF-06480605, PF06480605)

Catalog No. T9901A-353 Copy Product Info
Purity: 95%
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Afimkibart (PF06480605) is a humanised monoclonal antibody targeting TL1A (TNF-like Ligand 1A), which blocks TL1A-DR3 (death domain receptor 3) signalling on restrictive immune cells and fibroblasts. It can be used for inflammatory bowel disease and ulcerative colitis.

Afimkibart

Copy Product Info
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Catalog No. T9901A-353
Synonyms RVT-3101, RVT3101, PF-06480605, PF06480605

Afimkibart (PF06480605) is a humanised monoclonal antibody targeting TL1A (TNF-like Ligand 1A), which blocks TL1A-DR3 (death domain receptor 3) signalling on restrictive immune cells and fibroblasts. It can be used for inflammatory bowel disease and ulcerative colitis.

Afimkibart
Cas No. 2911580-96-4
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$247-In Stock
5 mg$747-In Stock
10 mg$1,190-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.2% (SDS-PAGE); 95.3% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Afimkibart (PF06480605) is a humanised monoclonal antibody targeting TL1A (TNF-like Ligand 1A), which blocks TL1A-DR3 (death domain receptor 3) signalling on restrictive immune cells and fibroblasts. It can be used for inflammatory bowel disease and ulcerative colitis.
SynonymsRVT-3101, RVT3101, PF-06480605, PF06480605
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetTL1A
Chemical Properties
Molecular Weight146.20 kDa
Cas No.2911580-96-4
Relative Density.no data available
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice.

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