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Tidutamab
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Catalog No. T76980Cas No. 2148354-90-7
Alias XmAb-18087, XmAb18087
Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T-cell binding domain (CD3) with antitumor activity for the study of gastric neurosecretory tumors.
Tidutamab
Tidutamab
😃Good
Catalog No. T76980Alias XmAb-18087, XmAb18087Cas No. 2148354-90-7
Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T-cell binding domain (CD3) with antitumor activity for the study of gastric neurosecretory tumors.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $413 | In Stock | In Stock | |
| 5 mg | $1,230 | In Stock | In Stock | |
| 10 mg | $1,990 | - | In Stock | |
| 25 mg | $2,950 | - | In Stock | |
| 50 mg | $3,980 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:97.9% (SDS-PAGE); 97.8% (SEC-HPLC)
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| Description | Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T-cell binding domain (CD3) with antitumor activity for the study of gastric neurosecretory tumors. |
| Targets&IC50 | SSTR2+ CHO cells (human):2.2 μg/mL (ED50) |
| In vitro | Tidutamab was able to bind to human SSTR2+ CHO cells in the concentration range of 0-100,000 ng/mL with an ED50 value of 2.2 μg/mL and mediated the killing of SSTR2+ target cells by T cells. [1] |
| In vivo | In NSG mice, Tidutamab was able to stimulate killing of SSTR2+ A549 lung cancer tumors by human T cells after a single intraperitoneal injection at a dose of 3 mg/kg. [1] |
| Synonyms | XmAb-18087, XmAb18087 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | SSTR2 & CD3E |
| Molecular Weight | 197.74 kDa |
| Cas No. | 2148354-90-7 |
| Color | Transparent |
| Appearance | Liquid |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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