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Tidutamab
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Catalog No. T76980Cas No. 2148354-90-7
Alias XmAb-18087, XmAb18087
Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T-cell binding domain (CD3) with antitumor activity for the study of gastric neurosecretory tumors.
Tidutamab
Tidutamab
Copy Product Info😃Good
Catalog No. T76980Alias XmAb-18087, XmAb18087Cas No. 2148354-90-7
Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T-cell binding domain (CD3) with antitumor activity for the study of gastric neurosecretory tumors.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $413 | In Stock | In Stock | |
| 5 mg | $1,230 | In Stock | In Stock | |
| 10 mg | $1,990 | - | In Stock | |
| 25 mg | $2,950 | - | In Stock | |
| 50 mg | $3,980 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:97.9% (SDS-PAGE); 97.8% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T-cell binding domain (CD3) with antitumor activity for the study of gastric neurosecretory tumors. |
| Targets&IC50 | SSTR2+ CHO cells (human):2.2 μg/mL (ED50) |
| In vitro | Tidutamab was able to bind to human SSTR2+ CHO cells in the concentration range of 0-100,000 ng/mL with an ED50 value of 2.2 μg/mL and mediated the killing of SSTR2+ target cells by T cells. [1] |
| In vivo | In NSG mice, Tidutamab was able to stimulate killing of SSTR2+ A549 lung cancer tumors by human T cells after a single intraperitoneal injection at a dose of 3 mg/kg. [1] |
| Synonyms | XmAb-18087, XmAb18087 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | SSTR2 & CD3E |
| Molecular Weight | 197.74 kDa |
| Cas No. | 2148354-90-7 |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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