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Anti-Mouse CD8α Antibody (2.43)
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Catalog No. T9901A-146 Copy Product Info
Purity: 99%
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Anti-Mouse CD8α Antibody (2.43) is a murine-derived monoclonal antibody against CD8α. It can deplete CD8+ T cells and prolong the survival time of liver cell transplants. It can be used in immunological research.
Anti-Mouse CD8α Antibody
(2.43)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $73 | - | In Stock | |
| 5 mg | Preferential | - | In Stock | |
| 10 mg | Preferential | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99%
Appearance:Liquid
Color:Transparent
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| Description | Anti-Mouse CD8α Antibody (2.43) is a murine-derived monoclonal antibody against CD8α. It can deplete CD8+ T cells and prolong the survival time of liver cell transplants. It can be used in immunological research. |
| In vitro | Anti-Mouse CD8α Antibody (2.43)（10 μg/mL） was applied to murine splenocyte cultures to inhibit CD8⁺ T cell activity. This blockade enhanced miR-520b-mediated antitumor immune responses by altering macrophage polarization and promoting CD4⁺ T cell activation[1]. |
| In vivo | In a mouse subcutaneous tumor model, mice were administered miR-520b (20 μg, tail vein) and receivedAnti-Mouse CD8α Antibody (2.43)( 100 μg, intraperitoneal injection on day 3) to deplete CD8⁺ T cells. CD8⁺ T cell depletion impaired the tumor-suppressive effects of miR-520b, indicating the antibody effectively neutralized CD8⁺ T cell-mediated immunity in vivo[1]. |
| Clone | 2.43 |
| Reactivity | Mouse |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | CD8a |
| Molecular Weight | 150 kDa |
| Isotype | Rat IgG2b kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Anti-Mouse CD8α Antibody (2.43) in vivo | Anti-Mouse CD8α Antibody (2.43) in vitro | Anti-Mouse CD8α Antibody (2.43) molecular weight
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