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Anti-CD83 Antibody
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Catalog No. T9901A-1308 Copy Product Info
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Anti-CD83 Antibody is a humanized monoclonal antibody targeting CD83, a marker for mature dendritic cells (DCs). It interferes with immunomodulatory functions by specifically binding to the extracellular domain of CD83. The antibody works by depleting CD83+ cells or blocking costimulatory signals, serving as an advanced compound tool for studying immune tolerance induction, graft-versus-host disease (GvHD) suppression, and autoimmune disease treatment.
Anti-CD83 Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $278 | Inquiry | Inquiry | |
| 5 mg | $838 | Inquiry | Inquiry | |
| 10 mg | $1,330 | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
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| Description | Anti-CD83 Antibody is a humanized monoclonal antibody targeting CD83, a marker for mature dendritic cells (DCs). It interferes with immunomodulatory functions by specifically binding to the extracellular domain of CD83. The antibody works by depleting CD83+ cells or blocking costimulatory signals, serving as an advanced compound tool for studying immune tolerance induction, graft-versus-host disease (GvHD) suppression, and autoimmune disease treatment. |
| In vitro | In primary human and mouse dendritic cell cultures, Anti-CD83 Antibody (3E12) targeted mature DCs and inhibited their capacity to stimulate T cell responses [1]. |
| In vivo | In a mouse model of collagen-induced arthritis, systemic administration of Anti-CD83 Antibody (3E12) provided significant protection against joint inflammation and bone destruction [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | CD83 |
| Isotype | IgG2SA |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Anti-CD83 Antibody in vivo | Anti-CD83 Antibody in vitro
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