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Octaethylene glycol monododecyl ether

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Catalog No. T37871Cas No. 3055-98-9
Alias Lumisterol 3 (>90%), Cholecalciferol EP Impurity C, 9β,10α-Cholesta-5,7-dien-3β-ol

Octaethylene glycol monododecyl ether (C12E8) is a non-ionic surfactant and detergent, suitable for assisting LOX activity assays and membrane protein extraction.

Octaethylene glycol monododecyl ether

Octaethylene glycol monododecyl ether

😃Good
Purity: 97.30%
Catalog No. T37871Alias Lumisterol 3 (>90%), Cholecalciferol EP Impurity C, 9β,10α-Cholesta-5,7-dien-3β-olCas No. 3055-98-9
Octaethylene glycol monododecyl ether (C12E8) is a non-ionic surfactant and detergent, suitable for assisting LOX activity assays and membrane protein extraction.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$30-In Stock
50 mg$40-In Stock
100 mg$56-In Stock
200 mg$81-In Stock
1 mL x 10 mM (in DMSO)$44-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:97.30%
Appearance:Viscous
Color:Transparent
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Product Introduction

Bioactivity
Description
Octaethylene glycol monododecyl ether (C12E8) is a non-ionic surfactant and detergent, suitable for assisting LOX activity assays and membrane protein extraction.
Targets&IC50
MOLT-4 cells:59 μM
In vitro
Octaethylene glycol monododecyl ether (C12E8) is capable of dissolving the viral envelope of intact influenza virus particles. This solubilization process occurs as C12E8 molecules assemble around the membrane, eventually forming micelles that incorporate and remove lipid and protein components from the viral envelope.[1]
SynonymsLumisterol 3 (>90%), Cholecalciferol EP Impurity C, 9β,10α-Cholesta-5,7-dien-3β-ol
Chemical Properties
Molecular Weight538.75
FormulaC28H58O9
Cas No.3055-98-9
SmilesCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCO
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
Ethanol: 30 mg/mL (55.68 mM), Sonication is recommended.
PBS (pH 7.2): 1 mg/mL (1.86 mM), Sonication is recommended.
DMSO: 80 mg/mL (148.49 mM), Sonication is recommended.
DMF: 30 mg/mL (55.68 mM), Sonication is recommended.
H2O: ≥ 80 mg/mL, Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (6.13 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
PBS (pH 7.2)/Ethanol/DMF/DMSO
1mg5mg10mg50mg
1 mM1.8561 mL9.2807 mL18.5615 mL92.8074 mL
Ethanol/DMF/DMSO
1mg5mg10mg50mg
5 mM0.3712 mL1.8561 mL3.7123 mL18.5615 mL
10 mM0.1856 mL0.9281 mL1.8561 mL9.2807 mL
20 mM0.0928 mL0.4640 mL0.9281 mL4.6404 mL
50 mM0.0371 mL0.1856 mL0.3712 mL1.8561 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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