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L-Cystine disodium monohydrate
Catalog No. T213412 Copy Product Info
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L-Cystine disodium monohydrate is the orally active extracellular form of L-Cysteine found in plant and animal proteins. It enhances the expression of the Nrf2 protein and activates the Nrf2 transcription factor. Additionally, L-Cystine disodium monohydrate decreases the production of reactive oxygen species (ROS) and safeguards cells from oxidant or Doxorubicin-induced apoptosis. When used with L-theanine, it boosts the production of antigen-specific IgG by increasing glutathione (GSH) levels and Th2-mediated responses. L-Cystine disodium monohydrate shows potential for research into cystinosis and kidney stones.
L-Cystine disodium monohydrate
Copy Product Info🥰Excellent
Catalog No. T213412
L-Cystine disodium monohydrate is the orally active extracellular form of L-Cysteine found in plant and animal proteins. It enhances the expression of the Nrf2 protein and activates the Nrf2 transcription factor. Additionally, L-Cystine disodium monohydrate decreases the production of reactive oxygen species (ROS) and safeguards cells from oxidant or Doxorubicin-induced apoptosis. When used with L-theanine, it boosts the production of antigen-specific IgG by increasing glutathione (GSH) levels and Th2-mediated responses. L-Cystine disodium monohydrate shows potential for research into cystinosis and kidney stones.
L-Cystine disodium monohydrate
Cas No. 199329-53-8
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | L-Cystine disodium monohydrate is the orally active extracellular form of L-Cysteine found in plant and animal proteins. It enhances the expression of the Nrf2 protein and activates the Nrf2 transcription factor. Additionally, L-Cystine disodium monohydrate decreases the production of reactive oxygen species (ROS) and safeguards cells from oxidant or Doxorubicin-induced apoptosis. When used with L-theanine, it boosts the production of antigen-specific IgG by increasing glutathione (GSH) levels and Th2-mediated responses. L-Cystine disodium monohydrate shows potential for research into cystinosis and kidney stones. |
| In vitro | L-Cystine disodium monohydrate, at concentrations of 83 µM or 200 µM for durations of 24 or 72 hours, effectively reverses the growth inhibitory effects of Sulfasalazine and Erastin in Huh6 cells. Additionally, L-Cystine disodium monohydrate at 0.8 mM for 4 hours induces an increase in Nrf2 protein expression in a Keap1-dependent manner in HeLa cells. |
| In vivo | L-Cystine (280 mg/kg, oral, 11 days) disodium monohydrate alongside L-theanine partially enhances antigen-specific IgG production in mice, primarily by increasing levels of glutathione (GSH) and T helper 2 (Th2) response. Additionally, when L-Cystine (200 mg/kg, oral, 11 days) disodium monohydrate is given with L-theanine (80 mg/kg, oral, 11 days), it significantly reduces the serum IL-10/IFN-γ ratio in mice 6 hours after DNP-KLH antigen stimulation, but increases this ratio 24 hours post-stimulation. |
| Molecular Weight | 302.27 |
| Formula | C6H12N2Na2O5S2 |
| Cas No. | 199329-53-8 |
| Smiles | [O-]C([C@@H](N)CSSC[C@H](N)C([O-])=O)=O.[Na+].O.[Na+] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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