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Interleukin-8 (54-72) (human) TFA (Synonyms: IL-8 (54-72), CXCL8 (54-72), C-X-C Motif Chemokine Ligand (54-72))

Catalog No. T83712 Copy Product Info
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Interleukin-8 (IL-8) (54-72), a peptide comprising amino acids 54-72 from the mature IL-8 sequence and 81-99 from the pre-processed form, inhibits the flow-based adhesion of primary human neutrophils to human umbilical vein endothelial cells (HUVECs).

Interleukin-8 (54-72) (human) TFA

Copy Product Info
🥰Excellent
Catalog No. T83712
Synonyms IL-8 (54-72), CXCL8 (54-72), C-X-C Motif Chemokine Ligand (54-72)

Interleukin-8 (IL-8) (54-72), a peptide comprising amino acids 54-72 from the mature IL-8 sequence and 81-99 from the pre-processed form, inhibits the flow-based adhesion of primary human neutrophils to human umbilical vein endothelial cells (HUVECs).

Interleukin-8 (54-72) (human) TFA
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$76InquiryInquiry
5 mg$281InquiryInquiry
10 mg$525InquiryInquiry
25 mg$1,220InquiryInquiry
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Interleukin-8 (IL-8) (54-72), a peptide comprising amino acids 54-72 from the mature IL-8 sequence and 81-99 from the pre-processed form, inhibits the flow-based adhesion of primary human neutrophils to human umbilical vein endothelial cells (HUVECs).
SynonymsIL-8 (54-72), CXCL8 (54-72), C-X-C Motif Chemokine Ligand (54-72)
Chemical Properties
Molecular Weight2401.80
FormulaC107H173N33O30.XCF3COOH
SmilesO=C([C@@H](NC(C)=O)CCCCN)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CO)=O)CC(N)=O)=O)CCC(O)=O)=O)=O)CCCNC(N)=N)=O)CCCCN)=O)=O)=O)CCCCN)=O)CCC(O)=O)=O)C(C)C)=O)C(C)C)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)C(C)C)=O)CC2=CNC3=C2C=CC=C3)=O)CC(N)=O)=O)CCC(O)=O.OC(C(F)(F)F)=O
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mg/mL (4.16 mM), Sonication is recommended.
PBS pH 7.2: 5 mg/mL (2.08 mM), Sonication is recommended.
DMF: 1 mg/mL (0.42 mM), Sonication is recommended.

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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