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Anti-CD4 Antibody (TRX1)
(Synonyms: TRX1) Copy Product Info
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Synonyms: TRX1
Catalog No. T9901A-1414 Copy Product Info
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Anti-CD4 Antibody (TRX1) is a humanized, non-depleting monoclonal antibody targeting the CD4 receptor. The compound specifically binds to CD4 on T helper cells, inducing receptor down-modulation and T-cell anergy to establish immune tolerance without causing significant depletion of CD4+ T cells. It is utilized in clinical and experimental research for tolerance induction in autoimmune diseases and as an HIV entry inhibitor.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $398 | Inquiry | Inquiry | |
| 5 mg | $1,190 | Inquiry | Inquiry | |
| 10 mg | $1,890 | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Antibody Information
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| Description | Anti-CD4 Antibody (TRX1) is a humanized, non-depleting monoclonal antibody targeting the CD4 receptor. The compound specifically binds to CD4 on T helper cells, inducing receptor down-modulation and T-cell anergy to establish immune tolerance without causing significant depletion of CD4+ T cells. It is utilized in clinical and experimental research for tolerance induction in autoimmune diseases and as an HIV entry inhibitor. |
| In vitro | In ex vivo analysis of blood samples from treated subjects, Anti-CD4 Antibody (TRX1) caused a dose-dependent down-modulation of cell surface CD4 expression on lymphocytes [1]. |
| Synonyms | TRX1 |
| Clone | TRX1 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | CD4 |
| Isotype | IgG1 |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Anti-CD4 Antibody (TRX1) chemical structure | Anti-CD4 Antibody (TRX1) in vitro
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