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CDX-1140

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Catalog No. T9901A-1738

CDX-1140 is a human IgG2 CD40 agonist antibody. It activates dendritic (DC) and B cells and induces NF-kB stimulation in CD40-expressing reporter cell lines. CDX-1140 functions independently of Fc receptor binding and works synergistically with natural CD40L signaling. It exhibits both direct and immune-mediated antitumor activity, making it useful for lymphoma and solid tumor research.

CDX-1140

CDX-1140

😃Good
Catalog No. T9901A-1738
CDX-1140 is a human IgG2 CD40 agonist antibody. It activates dendritic (DC) and B cells and induces NF-kB stimulation in CD40-expressing reporter cell lines. CDX-1140 functions independently of Fc receptor binding and works synergistically with natural CD40L signaling. It exhibits both direct and immune-mediated antitumor activity, making it useful for lymphoma and solid tumor research.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mgInquiryInquiryInquiry
5 mgInquiryInquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
CDX-1140 is a human IgG2 CD40 agonist antibody. It activates dendritic (DC) and B cells and induces NF-kB stimulation in CD40-expressing reporter cell lines. CDX-1140 functions independently of Fc receptor binding and works synergistically with natural CD40L signaling. It exhibits both direct and immune-mediated antitumor activity, making it useful for lymphoma and solid tumor research.
Chemical Properties
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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