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ArMan is an aryl mannoside ligand that can be functionalized onto the surface of virus-like particles (VLPs) via click chemistry. VLPs can target DC-SIGN dendritic cells, promoting selective co-engagement of DC-SIGN and TLR7, and resulting in a TH1-type immune response. VLP-ArMan-OvaI/II significantly inhibits tumor growth in a mouse melanoma model.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
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| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | ArMan is an aryl mannoside ligand that can be functionalized onto the surface of virus-like particles (VLPs) via click chemistry. VLPs can target DC-SIGN dendritic cells, promoting selective co-engagement of DC-SIGN and TLR7, and resulting in a TH1-type immune response. VLP-ArMan-OvaI/II significantly inhibits tumor growth in a mouse melanoma model. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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