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ArMan is an aryl mannoside ligand that can be functionalized onto the surface of virus-like particles (VLPs) via click chemistry. VLPs can target DC-SIGN dendritic cells, promoting selective co-engagement of DC-SIGN and TLR7, and resulting in a TH1-type immune response. VLP-ArMan-OvaI/II significantly inhibits tumor growth in a mouse melanoma model.
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| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | ArMan is an aryl mannoside ligand that can be functionalized onto the surface of virus-like particles (VLPs) via click chemistry. VLPs can target DC-SIGN dendritic cells, promoting selective co-engagement of DC-SIGN and TLR7, and resulting in a TH1-type immune response. VLP-ArMan-OvaI/II significantly inhibits tumor growth in a mouse melanoma model. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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