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SBB-Analogue (GL13) Biotin

Name: SBB-Analogue (GL13) Biotin
Brand: TargetMol
SKU: T89396
Rating: 4.5 (1 reviews)

(Synonyms: Sudan Black B-Analogue (GL13) Biotin, SBB-A-B, GL13) Copy Product Info

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Synonyms: Sudan Black B-Analogue (GL13) Biotin, SBB-A-B, GL13

Catalog No. T89396 Copy Product Info

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The compound SBB-Analogue (GL13) Biotin (SBB-A-B) is formed by linking a derivative of Sudan Black B (SBB) with biotin. It effectively detects senescent cells, avoids false-positive SA-β-gal results caused by serum starvation or cell fusion, and is compatible with experimental techniques such as flow cytometry and immunofluorescence analysis.

Cas No. 2171036-89-6

Pack Size	Price	USA Stock	Global Stock	Quantity
10 mg	Inquiry	Inquiry	Inquiry
50 mg	Inquiry	Inquiry	Inquiry

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Solid

Color:Black

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Product Introduction

Bioactivity

Description	The compound SBB-Analogue (GL13) Biotin (SBB-A-B) is formed by linking a derivative of Sudan Black B (SBB) with biotin. It effectively detects senescent cells, avoids false-positive SA-β-gal results caused by serum starvation or cell fusion, and is compatible with experimental techniques such as flow cytometry and immunofluorescence analysis.
In vitro	Method: SBB-Analogue (GL13) Biotin was used to specifically stain and detect senescent cells containing lipofuscin. The cell types examined included U2OS hCdt1 Tet-ON, human diploid lung fibroblasts, HBEC-Cdc6 Tet-ON, and irradiated Saos2-p21WAF1/Cip1 cells. Result: SBB-Analogue (GL13) Biotin effectively stained and detected the aforementioned senescent cells, exhibiting higher sensitivity and lower background, and the detection results were completely consistent with established senescence markers[1].
Synonyms	Sudan Black B-Analogue (GL13) Biotin, SBB-A-B, GL13

Chemical Properties

Molecular Weight	698.84
Formula	C₃₉H₃₈N₈O₃S
Cas No.	2171036-89-6
Smiles	N(=N/C=1C2=C(C(/N=N/C3=CC=CC=C3)=CC1)C=CC=C2)\C=4C5=C6C(NC(COC(CCCC[C@H]7[C@@]8([C@](CS7)(NC(=O)N8)[H])[H])=O)(C)NC6=CC=C5)=CC4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Related Tags: SBB-Analogue (GL13) Biotin chemical structure | SBB-Analogue (GL13) Biotin in vitro | SBB-Analogue (GL13) Biotin formula | SBB-Analogue (GL13) Biotin molecular weight