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Deoxyvasicinone
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Catalog No. TN1570Cas No. 530-53-0
Alias Pegenone, 9-Oxodeoxypeganine
Deoxyvasicinone is a natural alkaloid that acts as an inhibitor of translation, SUMOylation modification, and 15-human lipoxygenase in eukaryotic organisms.
Deoxyvasicinone
🥰Excellent
Catalog No. TN1570Alias Pegenone, 9-OxodeoxypeganineCas No. 530-53-0
Deoxyvasicinone is a natural alkaloid that acts as an inhibitor of translation, SUMOylation modification, and 15-human lipoxygenase in eukaryotic organisms.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $222 | - | In Stock |
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Expected start date of shipmentUSA Warehouse [1-2 days] Global Warehouse [5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
| Description | Deoxyvasicinone is a natural alkaloid that acts as an inhibitor of translation, SUMOylation modification, and 15-human lipoxygenase in eukaryotic organisms. |
| Targets&IC50 | HCC827:0.75μM, MCF-7 cells:7.21 μM, HepG2 cells:5.7 μM |
| In vitro | Methods: Deoxyvasicinone (0-100 μM) was used to treat human liver cancer cells (HepG2), human breast cancer cells (MCF7) and human lung cancer cells (HCC827), and CCK8 was used to determine cytotoxicity. Results: The IC50 values of deoxyvasicinone against HepG2, MCF7 and HCC827 were 5.7, 7.21 and 0.75 μM, respectively. [2] |
| Synonyms | Pegenone, 9-Oxodeoxypeganine |
| Molecular Weight | 186.21 |
| Formula | C11H10N2O |
| Cas No. | 530-53-0 |
| Smiles | O=C1C=2C=CC=CC2N=C3N1CCC3 |
| Relative Density. | 1.36g/cm3 |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 40 mg/mL (214.81 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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