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Senlizumab
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Catalog No. T9901A-1404Cas No. 336128-48-4
Alias CDP-571, BAY-103356
Senlizumab is a human monoclonal antibody expressed in CHO cells that specifically targets TNFSF2 (Tumor Necrosis Factor-alpha, TNF-α). It features a huIgG4SP heavy chain and a huκ light chain, with a predicted molecular weight of 146.9 kDa. Senlizumab neutralizes the biological activity of TNF-α by blocking its interaction with TNF receptors, thereby inhibiting downstream pro-inflammatory signaling pathways. It serves as a valuable tool for research into autoimmune and inflammatory diseases. The recommended isotype control is Human IgG4 kappa, Isotype Control (HY-P99003).
Senlizumab
Senlizumab
Copy Product Info🥰Excellent
Catalog No. T9901A-1404Alias CDP-571, BAY-103356Cas No. 336128-48-4
Senlizumab is a human monoclonal antibody expressed in CHO cells that specifically targets TNFSF2 (Tumor Necrosis Factor-alpha, TNF-α). It features a huIgG4SP heavy chain and a huκ light chain, with a predicted molecular weight of 146.9 kDa. Senlizumab neutralizes the biological activity of TNF-α by blocking its interaction with TNF receptors, thereby inhibiting downstream pro-inflammatory signaling pathways. It serves as a valuable tool for research into autoimmune and inflammatory diseases. The recommended isotype control is Human IgG4 kappa, Isotype Control (HY-P99003).
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| Description | Senlizumab is a human monoclonal antibody expressed in CHO cells that specifically targets TNFSF2 (Tumor Necrosis Factor-alpha, TNF-α). It features a huIgG4SP heavy chain and a huκ light chain, with a predicted molecular weight of 146.9 kDa. Senlizumab neutralizes the biological activity of TNF-α by blocking its interaction with TNF receptors, thereby inhibiting downstream pro-inflammatory signaling pathways. It serves as a valuable tool for research into autoimmune and inflammatory diseases. The recommended isotype control is Human IgG4 kappa, Isotype Control (HY-P99003). |
| Synonyms | CDP-571, BAY-103356 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | TNFSF2/TNFa |
| Cas No. | 336128-48-4 |
| Isotype | IgG4 (S228P) |
| Recommended Isotype Control |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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