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DMA trihydrochloride

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Catalog No. T18982Cas No. 2095832-33-8

DMA trihydrochloride is a fluorescent agent (λex=340 nm, λem=478 nm).

DMA trihydrochloride

DMA trihydrochloride

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Catalog No. T18982Cas No. 2095832-33-8
DMA trihydrochloride is a fluorescent agent (λex=340 nm, λem=478 nm).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$405 days5 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
DMA trihydrochloride is a fluorescent agent (λex=340 nm, λem=478 nm).
Targets&IC50
MCF-7 cells:5.3 μM , HeLa cells:3.4 μM
In vitro
In the case of MCF7, the IC50 is observed at 5.3 μM for DMA. The IC50 determined in the case of HeLa is 3.4 μM for DMA.
Chemical Properties
Molecular Weight505.02
FormulaC27H29ClN6O2
Cas No.2095832-33-8
SmilesCl.Cl.Cl.COc1ccc(cc1OC)-c1nc2cc(ccc2[nH]1)-c1nc2cc(ccc2[nH]1)N1CCN(C)CC1
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 15.9 mg/mL (31.48 mM), Sonication and heating are recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.9801 mL9.9006 mL19.8012 mL99.0060 mL
5 mM0.3960 mL1.9801 mL3.9602 mL19.8012 mL
10 mM0.1980 mL0.9901 mL1.9801 mL9.9006 mL
20 mM0.0990 mL0.4950 mL0.9901 mL4.9503 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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