Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(+)-JQ1 maleimide, featuring a cysteine-reactive maleimide linked to the BRD4 ligand, JQ1, via a PEG2 linker, serves as a probe suitable for the COFFEE method (COvalent Functionalization Followed by E3 Electroporation). This approach facilitates the covalent attachment of (+)-JQ1 maleimide to VHL, followed by electroporation into live cells, where the E3 ligase complexes with intracellular BRD4 to prompt its degradation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | 35 days | $ 818.00 |
Description | (+)-JQ1 maleimide, featuring a cysteine-reactive maleimide linked to the BRD4 ligand, JQ1, via a PEG2 linker, serves as a probe suitable for the COFFEE method (COvalent Functionalization Followed by E3 Electroporation). This approach facilitates the covalent attachment of (+)-JQ1 maleimide to VHL, followed by electroporation into live cells, where the E3 ligase complexes with intracellular BRD4 to prompt its degradation. |
Molecular Weight | 724.27 |
Formula | C35H42ClN7O6S |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
(+)-JQ1 maleimide inhibitor inhibit