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Anti-MRSA agent 10 (Compound 2d) is a cephalosporin derivative with antibacterial properties. It displays minimal resistance and shows low cytotoxicity in HUVEC and HBZY-1 cells.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
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| 10 mg | Inquiry | Backorder | Backorder | |
| 50 mg | Inquiry | Backorder | Backorder |
| Description | Anti-MRSA agent 10 (Compound 2d) is a cephalosporin derivative with antibacterial properties. It displays minimal resistance and shows low cytotoxicity in HUVEC and HBZY-1 cells. |
| In vitro | Anti-MRSA agent 10 exhibits no significant cytotoxicity towards sheep red blood cells, HUVECs, and HBZY-1 cells, with a safe dosage greater than 128 μg/mL. It shows antibacterial activity against Gram-negative Stenotrophomonas maltophilia and Staphylococcus aureus, Gram-positive Escherichia coli and Stenotrophomonas maltophilia, and drug-resistant Staphylococcus aureus (MRSA), with MIC values of 0.7, 4, 8, 8, and 2-4 μg/mL, respectively. At concentrations of 0-128 μg/mL, Anti-MRSA agent 10 targets penicillin-binding protein (PBP), disrupting bacterial cell wall structure, promoting oxidative damage, and thereby inhibiting the respiration and viability of S. aureus. |
| Formula | C30H36F3N7O8S2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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