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Anti-MRSA agent 10
🥰Excellent
Catalog No. T209489
Anti-MRSA agent 10 (Compound 2d) is a cephalosporin derivative with antibacterial properties. It displays minimal resistance and shows low cytotoxicity in HUVEC and HBZY-1 cells.
Anti-MRSA agent 10
Anti-MRSA agent 10
🥰Excellent
Catalog No. T209489
Anti-MRSA agent 10 (Compound 2d) is a cephalosporin derivative with antibacterial properties. It displays minimal resistance and shows low cytotoxicity in HUVEC and HBZY-1 cells.
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Product Introduction
Bioactivity
Chemical Properties
| Description | Anti-MRSA agent 10 (Compound 2d) is a cephalosporin derivative with antibacterial properties. It displays minimal resistance and shows low cytotoxicity in HUVEC and HBZY-1 cells. |
| In vitro | Anti-MRSA agent 10 exhibits no significant cytotoxicity towards sheep red blood cells, HUVECs, and HBZY-1 cells, with a safe dosage greater than 128 μg/mL. It shows antibacterial activity against Gram-negative Stenotrophomonas maltophilia and Staphylococcus aureus, Gram-positive Escherichia coli and Stenotrophomonas maltophilia, and drug-resistant Staphylococcus aureus (MRSA), with MIC values of 0.7, 4, 8, 8, and 2-4 μg/mL, respectively. At concentrations of 0-128 μg/mL, Anti-MRSA agent 10 targets penicillin-binding protein (PBP), disrupting bacterial cell wall structure, promoting oxidative damage, and thereby inhibiting the respiration and viability of S. aureus. |
| Formula | C30H36F3N7O8S2 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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