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Diclofenac sodium (Standard) (Synonyms: Diclofenac sodium salt (Standard))

Catalog No. TMSM-0938 Copy Product Info
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Diclofenac sodium (Standard) is the reference standard of diclofenac sodium, suitable for quantitative analysis, quality control, biochemical experiments, and related research. Diclofenac sodium is a non-selective anti-inflammatory drug and a cyclooxygenase (COX) inhibitor. In CHO cells, its IC₅₀ values against human COX-1 and COX-2 are 4 nM and 1.3 nM, respectively; against ovine COX-1 and COX-2, they are 5.1 μM and 0.84 μM, respectively. In addition, diclofenac sodium induces apoptosis in neural stem cells by activating the caspase cascade.

Diclofenac sodium (Standard)

Copy Product Info
🥰Excellent
Catalog No. TMSM-0938
Synonyms Diclofenac sodium salt (Standard)

Diclofenac sodium (Standard) is the reference standard of diclofenac sodium, suitable for quantitative analysis, quality control, biochemical experiments, and related research. Diclofenac sodium is a non-selective anti-inflammatory drug and a cyclooxygenase (COX) inhibitor. In CHO cells, its IC₅₀ values against human COX-1 and COX-2 are 4 nM and 1.3 nM, respectively; against ovine COX-1 and COX-2, they are 5.1 μM and 0.84 μM, respectively. In addition, diclofenac sodium induces apoptosis in neural stem cells by activating the caspase cascade.

Diclofenac sodium (Standard)
Cas No. 15307-79-6
Other Forms of Diclofenac sodium (Standard):
Pack SizePriceUSA StockGlobal StockQuantity
10 mg$367-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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Appearance:Solid
Color:White
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Product Introduction

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Description
Diclofenac sodium (Standard) is the reference standard of diclofenac sodium, suitable for quantitative analysis, quality control, biochemical experiments, and related research. Diclofenac sodium is a non-selective anti-inflammatory drug and a cyclooxygenase (COX) inhibitor. In CHO cells, its IC₅₀ values against human COX-1 and COX-2 are 4 nM and 1.3 nM, respectively; against ovine COX-1 and COX-2, they are 5.1 μM and 0.84 μM, respectively. In addition, diclofenac sodium induces apoptosis in neural stem cells by activating the caspase cascade.
SynonymsDiclofenac sodium salt (Standard)
Chemical Properties
Molecular Weight318.13
FormulaC14H10Cl2NNaO2
Cas No.15307-79-6
SmilesO=C(CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC=C1)[O-].[Na+]
Relative Density.0.781 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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