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Daltroban

Name: Daltroban
Brand: TargetMol
SKU: T15049
Price: 53 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T15049Cas No. 79094-20-5

Alias SKF 96148, BM-13505

Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist. Daltroban shows protective effect in reperfusion injury. Daltroban increase intracellular calcium in vascular smooth muscle cells.

Daltroban

🥰Excellent

Purity: 99.49%

Catalog No. T15049Alias SKF 96148, BM-13505Cas No. 79094-20-5

Pack Size	Price	Availability
1 mg	$53	In Stock
5 mg	$131	In Stock
10 mg	$196	In Stock
25 mg	$328	In Stock
50 mg	$467	In Stock
100 mg	$636	In Stock
200 mg	$857	In Stock
1 mL x 10 mM (in DMSO)	$119	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.49%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist. Daltroban shows protective effect in reperfusion injury. Daltroban increase intracellular calcium in vascular smooth muscle cells.
In vivo	Daltroban (20 mg/kg per hour i.v.) reduces the ischaemia-induced rise in the ST segment and prevented the development of a Q-wave in the ECG during reperfusion, in comparison with vehicle (physiological saline)-treated cats. Daltroban (1 mg/kg; i.v.; per hour) exerts protective effect in reperfusion injury following acute myocardial ischemia in cats[2]. Daltroban protects the myocardium from ischaemic injury and that this effect involves prevention of ischaemia-induced leukocytosis[3].
Synonyms	SKF 96148, BM-13505

Chemical Properties

Molecular Weight	353.82
Formula	C₁₆H₁₆ClNO₄S
Cas No.	79094-20-5
Smiles	OC(=O)Cc1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1
Relative Density.	1.378 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (141.31 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8263 mL	14.1315 mL	28.2630 mL	141.3148 mL
5 mM	0.5653 mL	2.8263 mL	5.6526 mL	28.2630 mL
10 mM	0.2826 mL	1.4131 mL	2.8263 mL	14.1315 mL
20 mM	0.1413 mL	0.7066 mL	1.4131 mL	7.0657 mL
50 mM	0.0565 mL	0.2826 mL	0.5653 mL	2.8263 mL
100 mM	0.0283 mL	0.1413 mL	0.2826 mL	1.4131 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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