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Enavatuzumab
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Catalog No. T76865Cas No. 1062149-33-0
Alias PDL-192, PDL192, Anti-TNFRSF12A/TWEAKR/CD266 Reference Antibody, ABT-361, ABT361
Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting the TWEAK receptor (TWEAKR), with anti-tumor activity. It induces tumor growth inhibition by recruiting and activating myeloid effectors to kill tumor cells. It is used in late-stage solid tumor research.
Enavatuzumab
Enavatuzumab
😃Good
Catalog No. T76865Alias PDL-192, PDL192, Anti-TNFRSF12A/TWEAKR/CD266 Reference Antibody, ABT-361, ABT361Cas No. 1062149-33-0
Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting the TWEAK receptor (TWEAKR), with anti-tumor activity. It induces tumor growth inhibition by recruiting and activating myeloid effectors to kill tumor cells. It is used in late-stage solid tumor research.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $228 | In Stock | In Stock | |
| 5 mg | $622 | In Stock | In Stock | |
| 10 mg | $993 | - | In Stock | |
| 25 mg | $1,470 | - | In Stock | |
| 50 mg | $1,980 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.7% (SEC-HPLC)
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| Description | Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting the TWEAK receptor (TWEAKR), with anti-tumor activity. It induces tumor growth inhibition by recruiting and activating myeloid effectors to kill tumor cells. It is used in late-stage solid tumor research. |
| In vitro | Enavatuzumab has growth inhibiting activity in a wide range of cancer cell lines in vitro. Enavatuzumab (10 μg/mL) and cells incubated together for 24 hours resulted in significantly increased migration of immune effector cells to SN12C and A375 tumor cells. [1] |
| In vivo | Enavatuzumab achieved 70% tumor growth inhibition (TGI) in vivo against H358 tumors.[2] |
| Synonyms | PDL-192, PDL192, Anti-TNFRSF12A/TWEAKR/CD266 Reference Antibody, ABT-361, ABT361 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TNFRSF12A/TWEAKR/CD266 |
| Molecular Weight | 150 kDa |
| Cas No. | 1062149-33-0 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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