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Chamigrenal

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Catalog No. T3P2855Cas No. 19912-84-6

β-Chamigrenal has anti-inflammatory activity, it has inhibitory effects on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in RAW 264.7 macrophages. Chamigrenal shows platelet-activating factor antagonistic activity and the IC(50) value of 1.2x10(-4) M; it also exhibits weak cytotoxicity towards MCF-7 cells(IC50=30.50 uM).

Chamigrenal

Chamigrenal

😃Good
Purity: 99.31%
Catalog No. T3P2855Cas No. 19912-84-6
β-Chamigrenal has anti-inflammatory activity, it has inhibitory effects on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in RAW 264.7 macrophages. Chamigrenal shows platelet-activating factor antagonistic activity and the IC(50) value of 1.2x10(-4) M; it also exhibits weak cytotoxicity towards MCF-7 cells(IC50=30.50 uM).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$80-In Stock
5 mg$226-In Stock
10 mg$337-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.31%
Appearance:Viscous
Color:Transparent
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Product Introduction

Bioactivity
Description
β-Chamigrenal has anti-inflammatory activity, it has inhibitory effects on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in RAW 264.7 macrophages. Chamigrenal shows platelet-activating factor antagonistic activity and the IC(50) value of 1.2x10(-4) M; it also exhibits weak cytotoxicity towards MCF-7 cells(IC50=30.50 uM).
Chemical Properties
Molecular Weight218.33
FormulaC15H22O
Cas No.19912-84-6
SmilesCC1(C)C2(C(=C)CCC1)CCC(C=O)=CC2
Relative Density.0.97g/cm3
Storage & Solubility Information
Storagekeep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: 100 mg/mL (458.02 mM), Sonication and heating are recommended.
DMSO: 100 mg/mL (458.02 mM), Sonication and heating are recommended.
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM4.5802 mL22.9011 mL45.8022 mL229.0111 mL
5 mM0.9160 mL4.5802 mL9.1604 mL45.8022 mL
10 mM0.4580 mL2.2901 mL4.5802 mL22.9011 mL
20 mM0.2290 mL1.1451 mL2.2901 mL11.4506 mL
50 mM0.0916 mL0.4580 mL0.9160 mL4.5802 mL
100 mM0.0458 mL0.2290 mL0.4580 mL2.2901 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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