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Bongkrekic acid

Catalog No. T36067 CAS 11076-19-0

Synonyms: Bongkrek Acid

Bongkrekic acid (Bongkrekic Acid (ammonium salt)) is a mitochondrial toxin secreted by Burkholderia gladioli that inhibits adenine nucleotide translocase (ANT).Bongkrekic acid Bongkrekic acid Bongkrekic acid induces extracellular traps in neutrophils through signaling mediated by p38, ERK, PAD4, and P2X1.

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Bongkrekic acid, CAS 11076-19-0

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Bongkrek Acid
Molecular Weight	486.6
Formula	C28H38O7
CAS No.	11076-19-0

Storage

store at low temperature

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 80 mg/mL (164.40 mM), Sonication is recommended.

H2O: 1 mg/mL

References and Literature

1. Anwar M,et al. Bongkrekic Acid-a Review of a Lesser-Known Mitochondrial Toxin. J Med Toxicol. 2017 Jun;13(2):173-179. doi: 10.1007/s13181-016-0577-Epub 2017 Jan 19. 2. Han D, et al. Bongkrekic Acid and Burkholderia gladioli pathovar cocovenenans: Formidable Foe and Ascending Threat to Food Safety. Foods. 2023 Oct 26;12(21):3926. 3. Kano A,et al. Bongkrekic acid facilitates glycolysis in cultured cells and induces cell death under low glucose conditions. Biochem Biophys Rep. 2019 Aug 29;20:100683.

Citations

1. Li F, Liu H, Wu X, et al.Tetrathiomolybdate Decreases the Expression of Alkaline Phosphatase in Dermal Papilla Cells by Increasing Mitochondrial ROS Production.International Journal of Molecular Sciences.2023, 24(4): 3123.

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Keywords

Bongkrekic acid 11076-19-0 Chromatin/Epigenetic MAPK Membrane transporter/Ion channel Neuroscience ERK P2X Receptor p38 MAPK PAD Bongkrek Acid inhibitor inhibit

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